Four ionones and ionone glycosides from the whole plant of Rehmannia piasezkii

被引：4
作者：
Zhou, Jie [1 ]
Shi, Guo-Ru [1 ]
Zhang, Wan-Qi [1 ]
Chen, Ruo-Yun [1 ]
Liu, Yan-Fei [1 ]
Yu, De-Quan [1 ]
机构：
[1] Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2022年 / 24卷 / 10期
关键词：
Scrophulariaceae; Rehmannia piasezkii; ionone; bioactivity; IRIDOID GLYCOSIDES; ROOTS;
D O I：
10.1080/10286020.2022.2097079
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Four new ionones and ionone glycosides (1-4) were isolated from the whole plant of Rehmannia piasezkii Maxim. Their planar structures as well as absolute configuration were confirmed via spectroscopic analysis, ECD calculation, and X-ray crystallography. Compounds 1-4 were tested for their cytotoxicity against five human tumor cell lines and ability to inhibit LPS-activated NO production in the BV2 cell line.
引用
收藏
页码：955 / 962
页数：8
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