Anti-Fatigue Activity of Extracts of Stem Bark from Acanthopanax senticosus

被引：76
作者：
Zhang, Xue-Ling [1 ]
Ren, Feng [1 ]
Huang, Wei [1 ]
Ding, Ren-Tao [1 ]
Zhou, Qiu-Sheng [2 ]
Liu, Xin-Wei [3 ]
机构：
[1] Zhengzhou Univ, Coll Phys Educ, Zhengzhou 450044, Peoples R China
[2] Henan Ball Games Management Ctr, Zhengzhou 450044, Peoples R China
[3] Henan Res Inst Sport Sci, Zhengzhou 450044, Peoples R China
来源：
MOLECULES | 2011年 / 16卷 / 01期
关键词：
anti-fatigue; Acanthopanax senticosus; forced swimming test; mice; EXERCISE-INDUCED FATIGUE; ENDURANCE EXERCISE; LIPID-PEROXIDATION; PHYSICAL STAMINA; MICE; ANTIOXIDANT; ANTIFATIGUE; HARMS; ANTISTRESS; CAPACITY;
D O I：
10.3390/molecules16010028
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In the present study, we investigated the anti-fatigue activity in male Kunming mice of extracts of stem bark from Acanthopanax senticosus (ASSE) using a forced swimming test. Mice were divided into four groups (three ASSE administered groups and the control group). The control group were gavaged with distilled water and ASSE administered groups were gavaged with ASSE (100, 200 and 400 mg/kg). After four weeks, a forced swimming test was performed and the biochemical parameters related to fatigue were examined. The results suggested that ASSE could extend the swimming time to exhaustion of the mice, as well as increase the tissue glycogen contents, while decreasing the blood lactate and serum urea nitrogen contents. This indicated that ASSE had anti-fatigue activity and could elevate the exercise tolerance.
引用
收藏
页码：28 / 37
页数：10
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