Iridium(iii) complexes as mitochondrial topoisomerase inhibitors against cisplatin-resistant cancer cells

被引：17
作者：
He, Liting [1 ]
Xiong, Kai [1 ]
Wang, Lili [1 ]
Guan, Ruilin [1 ]
Chen, Yu [1 ]
Ji, Liangnian [1 ]
Chao, Hui [1 ]
机构：
[1] Sun Yat Sen Univ, Sch Chem, MOE Key Lab Bioinorgan & Synthet Chem, Guangzhou 510275, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 67期
基金：
中国国家自然科学基金;
关键词：
34;
D O I：
10.1039/d1cc02178h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we developed the first metal-based mitochondrial topoisomerase inhibitors to achieve an effective therapeutic outcome for the therapy of cisplatin-resistant tumour cells.
引用
收藏
页码：8308 / 8311
页数：4
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