A photoredox catalyzed iminyl radical-triggered C-C bond cleavage/addition/Kornblum oxidation cascade of oxime esters and styrenes: synthesis of ketonitriles

被引：87

作者：

He, Bin-Qing ^{[1
]}

Yu, Xiao-Ye ^{[1
]}

Wang, Peng-Zi ^{[1
]}

Chen, Jia-Rong ^{[1
]}

Xiao, Wen-Jing ^{[1
,2
]}

机构：

[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, CCNU uOttawa Joint Res Ctr, Minist Educ,Coll Chem, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China

[2] Huanggang Normal Univ, Hubei Key Lab Proc & Applicat Catalyt Mat, Huanggang 438000, Hubei, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 86期

关键词：

CARBOXYLIC-ACIDS; FACILE SYNTHESIS; GENERATION; DIFUNCTIONALIZATION; FUNCTIONALIZATION; CYANOALKYLATION; FRAGMENTATION; DERIVATIVES; CHEMISTRY; NITRILES;

D O I：

10.1039/c8cc07072e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A photoredox-catalyzed iminyl radical-triggered C-C bond cleavage/addition/Kornblum oxidation cascade of cycloketone oxime esters and styrenes in DMSO is described. This three-component, one-pot procedure features mild conditions, a broad substrate scope, and high functional group tolerance, providing an efficient approach to access diversely functionalized ketonitriles.

引用

页码：12262 / 12265

页数：4

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