A photoredox catalyzed iminyl radical-triggered C-C bond cleavage/addition/Kornblum oxidation cascade of oxime esters and styrenes: synthesis of ketonitriles

被引：83
作者：
He, Bin-Qing [1 ]
Yu, Xiao-Ye [1 ]
Wang, Peng-Zi [1 ]
Chen, Jia-Rong [1 ]
Xiao, Wen-Jing [1 ,2 ]
机构：
[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, CCNU uOttawa Joint Res Ctr, Minist Educ,Coll Chem, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China
[2] Huanggang Normal Univ, Hubei Key Lab Proc & Applicat Catalyt Mat, Huanggang 438000, Hubei, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 86期
关键词：
CARBOXYLIC-ACIDS; FACILE SYNTHESIS; GENERATION; DIFUNCTIONALIZATION; FUNCTIONALIZATION; CYANOALKYLATION; FRAGMENTATION; DERIVATIVES; CHEMISTRY; NITRILES;
D O I：
10.1039/c8cc07072e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A photoredox-catalyzed iminyl radical-triggered C-C bond cleavage/addition/Kornblum oxidation cascade of cycloketone oxime esters and styrenes in DMSO is described. This three-component, one-pot procedure features mild conditions, a broad substrate scope, and high functional group tolerance, providing an efficient approach to access diversely functionalized ketonitriles.
引用
收藏
页码：12262 / 12265
页数：4
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