Bone Marrow Donors Worldwide and cord blood stem cell transplantation

被引:0
作者
van Rood, JJ
Schipper, RF
Bakker, JNA
van der Zanden, HGM
Oudshoorn, M
机构
[1] Univ Leiden Hosp, Dept Immunohematol & Blood Bank, NL-2300 RC Leiden, Netherlands
[2] Univ Leiden Hosp, Europdonor Fdn, NL-2300 RC Leiden, Netherlands
关键词
HLA matching; bone marrow transplantation; stem cell donors; cord blood transplantation; stem cell transplantation;
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Stem cell transplantation using cord blood donors mismatched for one or two HLA antigens can be successful. A simulation study was performed to assess the percentage of patients for whom a matched and/or a one or two antigen mismatched donor is available, Using either bone marrow donors worldwide (BMDW) (n = 925 109) or the cord blood donor file in BMDW (n = 11 049). As a donor source, for 97% of the Dutch patients a 0 or 1 antigen mismatched cord blood donor was available, for patients from the minority groups this percentage was 55%, These percentages compare favourably with the fraction of 0 mismatched donors found in BMDW.
引用
收藏
页码:S19 / S21
页数:3
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