Review of new antiepileptic drugs as initial therapy

被引:13
|
作者
Gil-Nagel, A [1 ]
机构
[1] Hosp Ruber Int, Serv Neurol, Programa Epilepsia, Madrid 28034, Spain
关键词
epilepsy; gabapentin; lamotrigine; topiramate; oxcarbazepine;
D O I
10.1046/j.1528-1157.44.s4.5.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The new onset of epilepsy usually leads to initiation of treatment with antiepileptic drugs (AEDs). Selection of the appropriate drug in this clinical situation is usually based on several factors, including efficacy for the suspected epilepsy type, tolerability, acute and long-term idiosyncratic side effects, pharma-cokinetic interactions, possibility of rapid titration, formulation, and expense. Over the last several years, the choices for treatment in newly diagnosed epilepsy have increased because a number of new AEDs have been approved for use in monotherapy. This article reviews randomized, controlled studies that have evaluated the use of new AEDs in monotherapy.
引用
收藏
页码:3 / 10
页数:8
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