Direct phosphorylation of N-protected imidazoles and benzoimidazoles -: A route to 1H-imidazol(benzoimidazol)-2-yl phosphonic and phosphinic acids and their derivatives

被引：10

作者：

Komarov, IV

Strizhak, AV

Kornilov, MY

Kostyuk, AN

Tolmachev, AA

机构：

[1] Kiev Taras Shevchenko Univ, Dept Chem, UA-252033 Kiev, Ukraine

[2] Natl Acad Sci Ukraine, Inst Organ Chem, UA-252094 Kiev, Ukraine

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 13期

关键词：

D O I：

10.1080/00397919808004288

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetic approaches to 1H-imidazol-2-yl and 1H-benzoimidazol-2-yl phosphinic and phosphonic acids and their derivatives are reported, based on phosphorylation of N-protected heterocylcles by PhPOCl2 or MePOCl2. Reaction of N-alkylbenzoimidazoles with POCl3 did not lead to C-phosphorylated products in a reasonable yield, [2,2']-bis-benzoimidazolyles being formed instead.

引用

页码：2355 / 2370

页数：16