Merodrimanes and other constituents from Talaromyces thailandiasis

被引：51

作者：

Dethoup, Tida

Manoch, Leka

Kijjoa, Anake

Pinto, Madalena

Gales, Luis

Damas, Ana Margarida

Silva, Artur M. S.

Eaton, Graham

Herz, Werner ^{[1
]}

机构：

[1] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA

[2] Kasetsart Univ, Fac Agr, Dept Plant Pathol, Bangkok, Thailand

[3] Univ Porto, Inst Ciencias Biol, ICBAS, P-4099003 Oporto, Portugal

[4] Univ Porto, CIIMAR, P-4099003 Oporto, Portugal

[5] Univ Porto, Fac Farm, CEQOFFUP, Ctr Estudo Quim Organ Fitoquim & Farmacol, P-4050047 Oporto, Portugal

[6] Univ Porto, IBMC, ICBAS, P-4094003 Oporto, Portugal

[7] Univ Porto, IBMC, Unidade Estructura Mol, P-4094003 Oporto, Portugal

[8] Univ Aveiro, Dept Quim, P-48101933 Aveiro, Portugal

[9] Univ Leicester, Dept Chem, Leicester LE 7RH, Leics, England

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 07期

关键词：

D O I：

10.1021/np0680578

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chemical study of a previously undescribed fungus, Talaromyces thailandiasis, furnished the two new merodrimanes thailandolides A (1) and B (2), an O-methylated derivative (3) of the aromatic fragment incorporated in thailandolide B, and three known closely related 1(3H)-isobenzofuran derivatives, penisimplicissin (4a), vermistatin (4b), and hydroxydihydrovermistatin (4c). Structures were established by spectroscopic measurements and confirmed by X-ray analyses of compounds 1 and 4b. The unusual peptide analogue N-benzoylphenylalanyl-N-benzoylphenyl alaninate (5) isolated earlier from a higher plant was also found.

引用

页码：1200 / 1202

页数：3

共 17 条

[1] Funicone-related compounds, potentiators of antifungal miconazole activity, produced by Talaromyces flavus FKI-0076 [J].