Preparation and characterization of calcium phosphate-albumin colloidal particles by high ultrasonic irradiation

被引:12
作者
Han, YC [1 ]
Li, SP [1 ]
Wang, XY [1 ]
Cao, XY [1 ]
Jia, L [1 ]
Li, JH [1 ]
机构
[1] Wuhan Univ Technol, Biomed Mat & Engn Ctr, Wuhan 430070, Peoples R China
关键词
calcium phosphate; bovine serum albumin; ultrasonic irradiation;
D O I
10.1007/s00396-005-1317-2
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Using high intensity ultrasonic irradiation, we prepared calcium phosphate-albumin colloidal particles from aqueous solutions of Ca(H2PO4)(2) and Ca(OH)(2) in the presence of bovine serum albumin (BSA). The effect of concentration of BSA (2-5 g/L) properties of the colloidal particles was studied at constant temperature. The effect of a resting period on the size distribution of the colloidal particles was also investigated. Morphology, phase composition, average diameter, size distribution and zeta potential were obtained by transmission electron microscopy, X-ray diffraction, particle size determination by PCS and electrokinetic measurements.
引用
收藏
页码:203 / 207
页数:5
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