共 26 条
Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity
被引:159
作者:

Dillon, Laura W.
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Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Kumar, Pankaj
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Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Shibata, Yoshiyuki
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Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Wang, Yuh-Hwa
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Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Willcox, Smaranda
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Univ N Carolina, Dept Microbiol & Immunol, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27514 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Griffith, Jack D.
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Univ N Carolina, Dept Microbiol & Immunol, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27514 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Pommier, Yves
论文数: 0 引用数: 0
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机构:
NCI, Lab Mol Pharmacol, NIH, Bethesda, MD 20892 USA
NCI, Dev Therapeut Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Takeda, Shunichi
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h-index: 0
机构:
Kyoto Univ, Japan Sci & Technol Corp, CREST Res Project, Radiat Genet,Fac Med,Sakyo Ku, Yoshida, Kyoto 6068501, Japan Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

Dutta, Anindya
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h-index: 0
机构:
Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA
机构:
[1] Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA
[2] Univ N Carolina, Dept Microbiol & Immunol, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27514 USA
[3] NCI, Lab Mol Pharmacol, NIH, Bethesda, MD 20892 USA
[4] NCI, Dev Therapeut Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
[5] Kyoto Univ, Japan Sci & Technol Corp, CREST Res Project, Radiat Genet,Fac Med,Sakyo Ku, Yoshida, Kyoto 6068501, Japan
关键词:
STRAND BREAK REPAIR;
HOMOLOGOUS RECOMBINATION;
VERTEBRATE CELLS;
HUMAN GENOME;
R-LOOPS;
DNA;
INSTABILITY;
TERMINATION;
EXPRESSION;
INTEGRITY;
D O I:
10.1016/j.celrep.2015.05.020
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
MicroDNAs are <400-base extrachromosomal circles found in mammalian cells. Tens of thousands of microDNAs have been found in all tissue types, including sperm. MicroDNAs arise preferentially from areas with high gene density, GC content, and exon density from promoters with activating chromatin modifications and in sperm from the 5'-UTR of full-length LINE-1 elements, but are depleted from lamin-associated heterochromatin. Analysis of microDNAs from a set of human cancer cell lines revealed lineage-specific patterns of microDNA origins. A survey of microDNAs from chicken cells defective in various DNA repair proteins reveals that homologous recombination and non-homologous end joining repair pathways are not required for microDNA production. Deletion of the MSH3 DNA mismatch repair protein results in a significant decrease in microDNA abundance, specifically from non-CpG genomic regions. Thus, microDNAs arise as part of normal cellular physiology-either from DNA breaks associated with RNA metabolism or from replication slippage followed by mismatch repair.
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收藏
页码:1749 / 1759
页数:11
相关论文
共 26 条
[1]
DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair
[J].
Adachi, N
;
Ishino, T
;
Ishii, Y
;
Takeda, S
;
Koyama, H
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2001, 98 (21)
:12109-12113

Adachi, N
论文数: 0 引用数: 0
h-index: 0
机构: Yokohama City Univ, Kihara Inst Biol Res, Grad Sch Integrated Sci, Totsuka Ku, Yokohama, Kanagawa 2440813, Japan

Ishino, T
论文数: 0 引用数: 0
h-index: 0
机构: Yokohama City Univ, Kihara Inst Biol Res, Grad Sch Integrated Sci, Totsuka Ku, Yokohama, Kanagawa 2440813, Japan

Ishii, Y
论文数: 0 引用数: 0
h-index: 0
机构: Yokohama City Univ, Kihara Inst Biol Res, Grad Sch Integrated Sci, Totsuka Ku, Yokohama, Kanagawa 2440813, Japan

Takeda, S
论文数: 0 引用数: 0
h-index: 0
机构: Yokohama City Univ, Kihara Inst Biol Res, Grad Sch Integrated Sci, Totsuka Ku, Yokohama, Kanagawa 2440813, Japan

Koyama, H
论文数: 0 引用数: 0
h-index: 0
机构: Yokohama City Univ, Kihara Inst Biol Res, Grad Sch Integrated Sci, Totsuka Ku, Yokohama, Kanagawa 2440813, Japan
[2]
Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability
[J].
Beckmann, Jacques S.
;
Estivill, Xavier
;
Antonarakis, Stylianos E.
.
NATURE REVIEWS GENETICS,
2007, 8 (08)
:639-646

Beckmann, Jacques S.
论文数: 0 引用数: 0
h-index: 0
机构: Univ Lausanne, Dept Med Genet, CH-1011 Lausanne, Switzerland

Estivill, Xavier
论文数: 0 引用数: 0
h-index: 0
机构: Univ Lausanne, Dept Med Genet, CH-1011 Lausanne, Switzerland

Antonarakis, Stylianos E.
论文数: 0 引用数: 0
h-index: 0
机构: Univ Lausanne, Dept Med Genet, CH-1011 Lausanne, Switzerland
[3]
Reduced X-ray resistance and homologous recombination frequencies in a RAD54(-/-) mutant of the chicken DT40 cell line
[J].
Bezzubova, O
;
Silbergleit, A
;
YamaguchiIwai, Y
;
Takeda, S
;
Buerstedde, JM
.
CELL,
1997, 89 (02)
:185-193

Bezzubova, O
论文数: 0 引用数: 0
h-index: 0
机构:
KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN

Silbergleit, A
论文数: 0 引用数: 0
h-index: 0
机构:
KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN

YamaguchiIwai, Y
论文数: 0 引用数: 0
h-index: 0
机构:
KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN

Takeda, S
论文数: 0 引用数: 0
h-index: 0
机构:
KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN

Buerstedde, JM
论文数: 0 引用数: 0
h-index: 0
机构:
KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN KYOTO UNIV, SCH MED, BAYER CHAIR DEPT MOL IMMUNOL, KYOTO 606, JAPAN
[4]
DEVELOPMENTAL AND CELL-TYPE SPECIFICITY OF LINE-1 EXPRESSION IN MOUSE TESTIS - IMPLICATIONS FOR TRANSPOSITION
[J].
BRANCIFORTE, D
;
MARTIN, SL
.
MOLECULAR AND CELLULAR BIOLOGY,
1994, 14 (04)
:2584-2592

BRANCIFORTE, D
论文数: 0 引用数: 0
h-index: 0
机构:
UNIV COLORADO,SCH MED,DEPT CELLULAR & STRUCT BIOL,BOX B111,4200 E 9TH AVE,DENVER,CO 80262 UNIV COLORADO,SCH MED,DEPT CELLULAR & STRUCT BIOL,BOX B111,4200 E 9TH AVE,DENVER,CO 80262

MARTIN, SL
论文数: 0 引用数: 0
h-index: 0
机构:
UNIV COLORADO,SCH MED,DEPT CELLULAR & STRUCT BIOL,BOX B111,4200 E 9TH AVE,DENVER,CO 80262 UNIV COLORADO,SCH MED,DEPT CELLULAR & STRUCT BIOL,BOX B111,4200 E 9TH AVE,DENVER,CO 80262
[5]
Extrachromosomal Circular DNA in Eukaryotes: Possible Involvement in the Plasticity of Tandem Repeats
[J].
Cohen, S.
;
Segal, D.
.
CYTOGENETIC AND GENOME RESEARCH,
2009, 124 (3-4)
:327-338

Cohen, S.
论文数: 0 引用数: 0
h-index: 0
机构:
Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel

Segal, D.
论文数: 0 引用数: 0
h-index: 0
机构:
Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel
[6]
Recurrent DNA inversion rearrangements in the human genome
[J].
Flores, Margarita
;
Morales, Lucia
;
Gonzaga-Jauregui, Claudia
;
Dominguez-Vidana, Rocio
;
Zepeda, Cinthya
;
Yanez, Omar
;
Gutierrez, Maria
;
Lemus, Tzitziki
;
Valle, David
;
Avila, Ma. Carmen
;
Blanco, Daniel
;
Medina-Ruiz, Sofia
;
Meza, Karla
;
Ayala, Erandi
;
Garcia, Delfino
;
Bustos, Patricia
;
Gonzalez, Victor
;
Girard, Lourdes
;
Tusie-Luna, Teresa
;
Davila, Guillermo
;
Palacios, Rafael
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2007, 104 (15)
:6099-6106

Flores, Margarita
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Morales, Lucia
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Gonzaga-Jauregui, Claudia
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Dominguez-Vidana, Rocio
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Zepeda, Cinthya
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Yanez, Omar
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Gutierrez, Maria
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Lemus, Tzitziki
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Valle, David
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Avila, Ma. Carmen
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Blanco, Daniel
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Medina-Ruiz, Sofia
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Meza, Karla
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Ayala, Erandi
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Garcia, Delfino
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Bustos, Patricia
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Gonzalez, Victor
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Girard, Lourdes
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Tusie-Luna, Teresa
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Davila, Guillermo
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico

Palacios, Rafael
论文数: 0 引用数: 0
h-index: 0
机构: Univ Nacl Autonoma Mexico, Ctr Ciencias Genom, Cuernavaca 62210, Morelos, Mexico
[7]
Human genetic variation and its contribution to complex traits
[J].
Frazer, Kelly A.
;
Murray, Sarah S.
;
Schork, Nicholas J.
;
Topol, Eric J.
.
NATURE REVIEWS GENETICS,
2009, 10 (04)
:241-251

Frazer, Kelly A.
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Translat Sci Inst, La Jolla, CA 92037 USA Scripps Translat Sci Inst, La Jolla, CA 92037 USA

Murray, Sarah S.
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Translat Sci Inst, La Jolla, CA 92037 USA

Schork, Nicholas J.
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Translat Sci Inst, La Jolla, CA 92037 USA

Topol, Eric J.
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Translat Sci Inst, La Jolla, CA 92037 USA
[8]
GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination
[J].
Ginno, Paul A.
;
Lim, Yoong Wearn
;
Lott, Paul L.
;
Korf, Ian
;
Chedin, Frederic
.
GENOME RESEARCH,
2013, 23 (10)
:1590-1600

Ginno, Paul A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA

Lim, Yoong Wearn
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA

Lott, Paul L.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA

Korf, Ian
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA
Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA

Chedin, Frederic
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA
Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA
[9]
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
[J].
Guelen, Lars
;
Pagie, Ludo
;
Brasset, Emilie
;
Meuleman, Wouter
;
Faza, Marius B.
;
Talhout, Wendy
;
Eussen, Bert H.
;
de Klein, Annelies
;
Wessels, Lodewyk
;
de Laat, Wouter
;
van Steensel, Bas
.
NATURE,
2008, 453 (7197)
:948-U83

Guelen, Lars
论文数: 0 引用数: 0
h-index: 0
机构:
Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

Pagie, Ludo
论文数: 0 引用数: 0
h-index: 0
机构:
Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

Brasset, Emilie
论文数: 0 引用数: 0
h-index: 0
机构:
Erasmus MC, Dept Cell Biol & Genet, NL-3000 CA Rotterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

Meuleman, Wouter
论文数: 0 引用数: 0
h-index: 0
机构:
Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands
Delft Univ Technol, Fac Elect Engn Math & Comp Sci, NL-2628 CD Delft, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

Faza, Marius B.
论文数: 0 引用数: 0
h-index: 0
机构:
Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

Talhout, Wendy
论文数: 0 引用数: 0
h-index: 0
机构:
Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

Eussen, Bert H.
论文数: 0 引用数: 0
h-index: 0
机构:
Erasmus MC, Dept Clin Genet, NL-3000 CA Rotterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

de Klein, Annelies
论文数: 0 引用数: 0
h-index: 0
机构:
Erasmus MC, Dept Clin Genet, NL-3000 CA Rotterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

论文数: 引用数:
h-index:
机构:

de Laat, Wouter
论文数: 0 引用数: 0
h-index: 0
机构:
Erasmus MC, Dept Cell Biol & Genet, NL-3000 CA Rotterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands

van Steensel, Bas
论文数: 0 引用数: 0
h-index: 0
机构:
Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands Netherlands Canc Inst, Div Mol Biol, NL-1066 CX Amsterdam, Netherlands
[10]
Similar effects of BRCA2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination
[J].
Hatanaka, A
;
Yamazoe, M
;
Sale, JE
;
Takata, M
;
Yamamoto, K
;
Kitao, H
;
Sonoda, E
;
Kikuchi, K
;
Yonetani, Y
;
Takeda, S
.
MOLECULAR AND CELLULAR BIOLOGY,
2005, 25 (03)
:1124-1134

Hatanaka, A
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Yamazoe, M
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Sale, JE
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Takata, M
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

论文数: 引用数:
h-index:
机构:

Kitao, H
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Sonoda, E
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Kikuchi, K
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Yonetani, Y
论文数: 0 引用数: 0
h-index: 0
机构: Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan

Takeda, S
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan Kyoto Univ, Dept Radiat Genet, Fac Med, Sakyo Ku, Kyoto 6068501, Japan