Influence of the difference in refractive index on the interface of an object and the surroundings in near-infrared fluorescence tomography

被引：2
作者：
Takematsu, Maho [1 ]
Umezawa, Masakazu [1 ]
Sera, Toshihiro [2 ]
Kitagawa, Yuichi [1 ]
Kurahashi, Hiroyuki [1 ]
Yamada, Shuta [1 ]
Okubo, Kyohei [1 ]
Kamimura, Masao [1 ]
Yokota, Hideo [3 ]
Soga, Kohei [1 ]
机构：
[1] Tokyo Univ Sci, Fac Adv Engn, Dept Mat Sci & Technol, 6-3-1 Niijuku, Tokyo 1258585, Japan
[2] Kyushu Univ, Fac Engn, Dept Mech Engn, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan
[3] RIKEN, Image Proc Team, Ctr Adv Photon, 2-1 Hirosawa, Wako, Saitama 3510198, Japan
来源：
APPLIED OPTICS | 2022年 / 61卷 / 02期
基金：
日本科学技术振兴机构;
关键词：
OPTICAL TOMOGRAPHY; EXPRESSION; WINDOW; LIGHT;
D O I：
10.1364/AO.445357
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
The refraction of fluorescence from the inside of a sample at the surface results in fluctuations in fluorescence computed tomography (CT). We evaluated the influence of the difference in refractive index (RI) between the sample body and the surroundings on fluorescence CT results. The brightest fluorescent point is away from the correct point on the tomograms owing to the refraction. The speculated position is determined as the exact point if the RI ratio ranges between 0.97 and 1.03 by immersing the body in an RI matching liquid. The results can help in experimental settings of fluorescence CT for acquiring three-dimensional positional information. (C) 2022 Optica Publishing Group
引用
收藏
页码：638 / 644
页数：7
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