Effective drift and diffusion of a particle jumping between mobile and immobile states

被引:6
作者
Berezhkovskii, Alexander M. [2 ]
Bezrukov, Sergey M. [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Lab Phys & Struct Biol, Program Phys Biol, NIH, Bethesda, MD 20892 USA
[2] NIH, Math & Stat Comp Lab, Div Computat Biosci, Ctr Informat Technol, Bethesda, MD 20892 USA
关键词
Stochastic transport; Effective propagator; INTEGRIN-CYTOSKELETAL INTERACTIONS; MIGRATING FIBROBLASTS; CHROMATOGRAPHY; MODEL;
D O I
10.1016/j.jelechem.2010.08.017
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We study propagation of a particle that jumps between two states, in which it moves with different velocities and diffusion coefficients. To simplify analysis, in the main part of the paper we derive formulas assuming that in one of the states the particle is immobile. A generalization to the case when the particle is mobile in both states is given at the end of the paper. The formulas show how the effective drift velocity and effective diffusion coefficient depend on jump rates between the two states as well as on the particle velocities and diffusion coefficients in these states. Specifically, we find that the effective diffusion coefficient can exhibit a non-monotonic behavior as a function of the ratio of the jump rates. Published by Elsevier B.V.
引用
收藏
页码:352 / 355
页数:4
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