Large fixed-size metal-on-metal total hip arthroplasty: higher serum metal ion levels in patients with pain

被引:13
|
作者
Smeekes, Christiaan [1 ,2 ]
Ongkiehong, Bastiaan [2 ]
van der Wal, Bart [2 ]
Wolterbeek, Ron [1 ]
Henseler, Jan-Ferdinand [1 ]
Nelissen, Rob [1 ]
机构
[1] Leiden Univ, Dept Orthopaed, Leiden, Netherlands
[2] Meander Med Ctr, Dept Orthopaed, Amersfoort, Netherlands
关键词
Total hip arthroplasty; Quality of life; Cobalt; Chromium; Pseudotumours; Revisions; FEMORAL-HEAD; GROIN PAIN; FAILURE; WEAR; REPLACEMENT; VALIDATION; DISABILITY; MINIMUM; COBALT; 28-MM;
D O I
10.1007/s00264-014-2605-6
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Purpose Recently, concerns have arisen about metal-on-metal (MoM) total hip arthroplasty (THA). Therefore, the purpose of this cross-sectional cohort study was to describe the incidence of pain, pseudotumours, revisions and the relation between elevated metal ion levels, functional outcome and quality of life after MoM THA. Methods In 351 patients, 377 MoM THA with a fixed-size 38-mm head were evaluated with a mean follow-up of 30 months (range 11-58). Evaluation included pain, serum metal ions, patient-reported questionnaires (Short Form-36 [SF-36], Hip disability and Osteoarthritis Outcome Score [HOOS] and the Oxford Hip Score [OHS]) and radiological imaging. Sixteen patients did not participate in the screening. Results One hundred and eighteen (35 %) patients reported pain and showed significantly higher cobalt and chromium levels compared to patients without pain. Median serum cobalt levels were 4.4 mu g/l (interquartile range [IQR] 6.6) and chromium levels were 3.6 mu g/l (IQR 4.8). Patients with cobalt levels of a parts per thousand currency sign5 mu g/l reported significantly better outcome on the SF-36 and HOOS. Fifty-seven pseudotumours were identified in 227 THAs. A revision rate of 19 % was observed. Conclusion In conclusion, 35 % of the patients experienced pain after MoM THA. These patients showed significantly higher serum metal ion levels. The patient-reported questionnaires indicated significantly better outcome in patients with cobalt levels a parts per thousand currency sign5 mu g/l.
引用
收藏
页码:631 / 638
页数:8
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