Intratympanic injection with dexamethasone for sudden sensorineural hearing loss

被引：26

作者：

Tsai, Y-J ^{[1
]}

Liang, J-G ^{[1
,2
]}

Wu, W-B

Ding, Y-F ^{[1
]}

Chiang, R. P-Y ^{[1
,3
]}

Wu, S-M ^{[1
]}

机构：

[1] Shin Kong Wu Ho Su Mem Hosp, Dept Otolaryngol, Taipei, Taiwan

[2] Puli Christian Hosp, Dept Otolaryngol, Nantou, Taiwan

[3] Fu Jen Catholic Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Taipei, Taiwan

来源：

JOURNAL OF LARYNGOLOGY AND OTOLOGY | 2011年 / 125卷 / 02期

关键词：

Sudden Sensorineural Hearing Loss; Dexamethasone; Intratympanic Therapy; Middle Ear; INNER-EAR; STEROIDS; THERAPY;

D O I：

10.1017/S0022215110002124

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Objective: To investigate the efficacy of intratympanic steroid therapy in adults with sudden sensorineural hearing loss, and to analyse the factors associated with treatment outcome. Design: Retrospective study of patients undergoing intratympanic steroid injection for sudden sensorineural hearing loss between 1 January 2006 and 30 June 2007 at a teaching hospital in Taipei, Taiwan. Results: Patients who received intratympanic steroid therapy within seven days of disease onset achieved a significantly better response rate (76.1 per cent), compared with the delayed treatment group (50 per cent). The total response rate, after four steroid injections, was 68.9 per cent. Patients with low and mid-frequency hearing loss were more responsive to steroid treatment. Vertigo was a negative prognostic factor for recovery. There were no long-term sequelae of intratympanic steroid treatment. Conclusion: Intratympanic steroid injection may be a simple and effective treatment for patients with sudden sensorineural hearing loss.

引用

页码：133 / 137

页数：5