Antibacterial activity of the Iraqi Rheum ribes root

被引：27

作者：

Alaadin, Alaadin M. ^{[1
]}

Al-Khateeb, Ekbal Hasan

Jager, Anna K.

机构：

[1] Hawler Med Univ, Coll Pharm, Dept Pharmacognosy, Erbil, Iraq

[2] Univ Baghdad, Coll Pharm, Dept Pharmacognosy, Baghdad, Iraq

[3] Danish Univ Pharmaceut Sci, Dept Med Chem, Copenhagen, Denmark

来源：

PHARMACEUTICAL BIOLOGY | 2007年 / 45卷 / 09期

关键词：

anthraquinones; antibacterial; emodin; Rheum ribes;

D O I：

10.1080/13880200701575049

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The antibacterial activity of the ethanol, aqueous, and organic extracts from the root of Rheum ribes Linn (Polygonaceae) was examined. Four anthraquinone aglycone components, chrysopahnol, physcion, aloe emodin, and emodin, were isolated from the biologically active extract and identified by spectroscopic analysis. Emodin is recorded for the first time in this species. The MIC values of the biologically active extracts, aloe emodin, and emodin, were 500, 125, 250, and 63 mu g/mL against Staphylococcus aureus, respectively. The extracts and compounds did not inhibit Pseudomonas aeruginosa and Escherichia coli at the highest concentration tested, 4000 and 250 mu g/mL, respectively.

引用

页码：688 / 690

页数：3

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