Mannich-type reaction promoted by an ionic liquid

被引:60
作者
Akiyama, T [1 ]
Suzuki, A [1 ]
Fuchibe, K [1 ]
机构
[1] Gakushuin Univ, Fac Sci, Dept Chem, Toshima Ku, Tokyo 1718588, Japan
关键词
ionic liquids; Mannich reaction; imine; catalysis;
D O I
10.1055/s-2005-864816
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The Mannich-type reaction of silyl enolates with aldimines occurred smoothly with [emim]OTf as a solvent and without the addition of an activator to afford beta-amino carbonyl compounds in excellent yields.
引用
收藏
页码:1024 / 1026
页数:3
相关论文
共 40 条
[1]   HCl-catalyzed stereoselective Mannich reaction in H2O-SDS system [J].
Akiyama, T ;
Matsuda, K ;
Fuchibe, K .
SYNLETT, 2005, (02) :322-324
[2]   Enantioselective Mannich-type reaction catalyzed by a chiral Bronsted acid [J].
Akiyama, T ;
Itoh, J ;
Yokota, K ;
Fuchibe, K .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (12) :1566-1568
[3]   Mannich-type reaction catalyzed by HBF4 in water:: Effect of the loading of surfactant [J].
Akiyama, T ;
Itoh, J ;
Fuchibe, K .
SYNLETT, 2002, (08) :1269-1272
[4]  
Akiyama T, 2002, ADV SYNTH CATAL, V344, P338, DOI 10.1002/1615-4169(200206)344:3/4<338::AID-ADSC338>3.0.CO
[5]  
2-O
[6]   A highly stereo-divergent Mannich-type reaction catalyzed by Bronsted acid in aqueous media [J].
Akiyama, T ;
Takaya, J ;
Kagoshima, H .
TETRAHEDRON LETTERS, 2001, 42 (24) :4025-4028
[7]  
Akiyama T, 1999, SYNLETT, P1426
[8]   HBF4 catalyzed Mannich-type reaction in aqueous media [J].
Akiyama, T ;
Takaya, J ;
Kagoshima, H .
SYNLETT, 1999, (07) :1045-1048
[9]  
Arend M, 1998, ANGEW CHEM INT EDIT, V37, P1044, DOI 10.1002/(SICI)1521-3773(19980504)37:8<1044::AID-ANIE1044>3.0.CO
[10]  
2-E