Study on the Antibacterial Activity of Immobilized Antibacterial Peptides on PET Nonwoven Fabrics

被引：0

作者：

Hao, Limei ^{[1
]}

Wang, Shuang

Hou, Lili

Wu, Jinhui ^{[1
]}

Yang, Jingquan ^{[1
]}

机构：

[1] Acad Mil Med Sci, Inst Med Equipment, Tianjin 300161, Peoples R China

来源：

PROCEEDINGS OF 2010 INTERNATIONAL CONFERENCE ON CHEMICAL ENGINEERING AND APPLICATIONS | 2010年

关键词：

PET Nonwoven Fabrics; Protamine sulfate; Polymyxin sulfate; Immobilization; antibacterial efficiency; PROTAMINE; POLY(ETHYLENE-TEREPHTHALATE); BACTERIA; HEPARIN; SURFACE;

D O I：

暂无

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Two novel antibacterial protective materials (abbr. Peptide-PET) were prepared by immobilizing antibacterial peptides (Protamine sulfate and Polymyxin sulfate) on polyethylene terephthalate (PET) nonwoven fabrics in this study. Surface modifications of the fabric were performed via chemically modified procedure: creating carboxyl groups onto PET surface, grafting coupling agent and immobilizing the Protamine sulfate or Polymyxin sulfate. Scanning electron microscopy (SEM) was used to analyze the surface morphology of the fabrics, Toluidine blue method and X ray photoelectron spectroscopy (XPS) method were used to evaluate grafting densities. The antibacterial activities of the two Peptide-PET fabrics were investigated by Liquid Droplet Method. The SEM pictures showed that there were not any changes on the surface of the blank fabrics and modified fabrics. The results of XPS confirmed that Protamine sulfate and Polymyxin sulfate were successfully grafted on the surface of PET fabrics. The results of antibacterial experiments showed that both of them had excellent antibacterial activity against Escherichia coli and Staphylococcus aureus.

引用

页码：19 / 25

页数：7

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