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Univ Bristol, Fac Med & Vet Sci, Dept Cellular & Mol Med, Canc Res UK,Colorectal Tumor Biol Res Grp, Bristol BS8 1TD, Avon, England Univ Bristol, Fac Med & Vet Sci, Dept Cellular & Mol Med, Canc Res UK,Colorectal Tumor Biol Res Grp, Bristol BS8 1TD, Avon, England