Anti-hyperglycemic effects of sugar maple Acer saccharum and its constituent acertannin

被引：39

作者：

Honma, Atsushi ^{[1
]}

Koyama, Tomoyuki ^{[1
]}

Yazawa, Kazunaga ^{[1
]}

机构：

[1] Tokyo Univ Marine Sci & Technol, Grad Sch Marine Sci & Technol, Lab Nutraceut & Funct Foods Sci, Minato Ku, Tokyo 1088477, Japan

来源：

FOOD CHEMISTRY | 2010年 / 123卷 / 02期

关键词：

Ater saccharum; Diabetes mellitus; alpha-Glucosidase inhibitory effect; Acertannin; 2,6-di-O-galloy1-1,5-anhydro-D-glucitol; ALPHA-GLUCOSIDASE; INHIBITORS; ANTIOXIDANT; EXTRACT; GALLATE; LEAVES;

D O I：

10.1016/j.foodchem.2010.04.052

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The anti-hyperglycemic effects of the leaves of sugar maple, Acer saccharum and purification and identification of the active compound were investigated. Extracts of the leaves showed a potent inhibitory effect on alpha-glucosidase in both in vivo and in vitro experiments. In vitro enzyme-inhibitory assay-guided fractionation of the crude extract gave active compound, acertannin (2,6-di-O-galloy1-1,5-anhydro-oglucitol) by spectroscopic analysis. This is the first report that acertannin from A. saccharum may be used in diabetes care. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：390 / 394

页数：5

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