Single laser source for multimodal coherent anti-Stokes Raman scattering microscopy

被引：16

作者：

Pegoraro, Adrian F. ^{[1
,2
]}

Slepkov, Aaron D. ^{[2
]}

Ridsdale, Andrew ^{[2
]}

Pezacki, John Paul ^{[2
]}

Stolow, Albert ^{[1
,2
]}

机构：

[1] Queens Univ, Dept Phys, Kingston, ON K7L 3N6, Canada

[2] Natl Res Council Canada, Steacie Inst Mol Sci, Ottawa, ON K1A 0R6, Canada

来源：

APPLIED OPTICS | 2010年 / 49卷 / 25期

基金：

加拿大自然科学与工程研究理事会;

关键词：

HIGH-SPECTRAL-RESOLUTION; LIGHT-SOURCE; IN-VIVO; 2-PHOTON FLUORESCENCE; CARS MICROSCOPY; SPECTROSCOPY; FIBER; MICROSPECTROSCOPY; PHOTODAMAGE; EXCITATION;

D O I：

10.1364/AO.49.000F10

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Short laser pulse technology has significantly contributed to biomedical research, especially via nonlinear optical microscopy. Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free, chemical-selective method that is growing in importance as improved methods and light sources develop. Here we discuss different approaches to laser source development for CARS microscopy and highlight the advantages of a multimodal CARS microscope, illustrated by selected applications in biomedical research. (c) 2010 Optical Society of America

引用

页码：F10 / F17

页数：8

共 54 条

[31] Compact coherent anti-Stokes Raman scattering microscope based on a picosecond two-color Er:fiber laser system [J].

Krauss, Guenther ;

Hanke, Tobias ;

Sell, Alexander ;

Traeutlein, Daniel ;

Leitenstorfer, Alfred ;

Selm, Romedi ;

Winterhalder, Martin ;

Zumbusch, Andreas .

OPTICS LETTERS, 2009, 34 (18) :2847-2849

[32] Label-free molecular imaging of atherosclerotic lesions using multimodal nonlinear optical microscopy [J].

Le, Thuc T. ;

Langohr, Ingeborg M. ;

Locker, Matthew J. ;

Sturek, Michael ;

Cheng, Ji-Xin .

JOURNAL OF BIOMEDICAL OPTICS, 2007, 12 (05)

[33] The role of backscattering in SHG tissue imaging [J].

Legare, Francois ;

Pfeffer, Christian ;

Olsen, Bjorn R. .

BIOPHYSICAL JOURNAL, 2007, 93 (04) :1312-1320

[34] Towards CARS endoscopy [J].

Légaré, François ;

Evans, Conor L. ;

Ganikhanov, Feruz ;

Xie, X. Sunney .

OPTICS EXPRESS, 2006, 14 (10) :4427-4432

[35] Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism [J].

Lyn, Rodney K. ;

Kennedy, David C. ;

Sagan, Selena M. ;

Blais, David R. ;

Rouleau, Yanouchka ;

Pegoraro, Adrian F. ;

Xie, X. Sunney ;

Stolow, Albert ;

Pezacki, John Paul .

VIROLOGY, 2009, 394 (01) :130-142

[36] Mitigating thermal mechanical damage potential during two-photon dermal imaging [J].

Masters, BR ;

So, PTC ;

Buehler, C ;

Barry, N ;

Sutin, JD ;

Mantulin, WW ;

Gratton, E .

JOURNAL OF BIOMEDICAL OPTICS, 2004, 9 (06) :1265-1270

[37] Imaging the thermodynamic state of lipid membranes with multiplex CARS microscopy [J].

Müller, M ;

Schins, JM .

JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (14) :3715-3723

[38] Intracellular imaging of HCV RNA and cellular lipids by using simultaneous two-photon fluorescence and coherent anti-Stokes Raman scattering microscopies [J].

Nan, Xiaolin ;

Tonary, Angela M. ;

Stolow, Albert ;

Xie, X. Sunney ;

Pezacki, John Paul .

CHEMBIOCHEM, 2006, 7 (12) :1895-1897

[39] ULTRAFAST NONLINEAR SPECTROSCOPY WITH CHIRPED OPTICAL PULSES [J].

NIBBERING, ETJ ;

WIERSMA, DA ;

DUPPEN, K .

PHYSICAL REVIEW LETTERS, 1992, 68 (04) :514-517

[40] Fourier-transform coherent anti-Stokes Raman scattering microscopy [J].

Ogilvie, JP ;

Beaurepaire, E ;

Alexandrou, A ;

Joffre, M .

OPTICS LETTERS, 2006, 31 (04) :480-482

← 1 2 3 4 5 6 →