Single laser source for multimodal coherent anti-Stokes Raman scattering microscopy

被引:16
作者
Pegoraro, Adrian F. [1 ,2 ]
Slepkov, Aaron D. [2 ]
Ridsdale, Andrew [2 ]
Pezacki, John Paul [2 ]
Stolow, Albert [1 ,2 ]
机构
[1] Queens Univ, Dept Phys, Kingston, ON K7L 3N6, Canada
[2] Natl Res Council Canada, Steacie Inst Mol Sci, Ottawa, ON K1A 0R6, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
HIGH-SPECTRAL-RESOLUTION; LIGHT-SOURCE; IN-VIVO; 2-PHOTON FLUORESCENCE; CARS MICROSCOPY; SPECTROSCOPY; FIBER; MICROSPECTROSCOPY; PHOTODAMAGE; EXCITATION;
D O I
10.1364/AO.49.000F10
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Short laser pulse technology has significantly contributed to biomedical research, especially via nonlinear optical microscopy. Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free, chemical-selective method that is growing in importance as improved methods and light sources develop. Here we discuss different approaches to laser source development for CARS microscopy and highlight the advantages of a multimodal CARS microscope, illustrated by selected applications in biomedical research. (c) 2010 Optical Society of America
引用
收藏
页码:F10 / F17
页数:8
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