Enantioseparations in capillary electromigration techniques: recent developments and future trends

被引:306
作者
Chankvetadze, B
Blaschke, G
机构
[1] Univ Munster, Inst Pharmaceut Chem, D-48149 Munster, Germany
[2] Tbilisi State Univ, Sch Chem, Mol Recognit & Separat Sci Lab, GE-380028 Tbilisi, Georgia
关键词
reviews; enantioseparations; chiral selectors; chiral stationary phases;
D O I
10.1016/S0021-9673(00)01124-9
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review summarizes the current status of enantioseparations using capillary electromigration techniques and gives the authors insights on the selected fundamental aspects and future trends in this held. The most recent developments in the held of chiral separations using capillary electrophoresis (CE) and capillary electrochromatography (CEC) are summarized. The status of chiral electromigration techniques is evaluated tacking into account the most recent developments in related techniques such as chiral HPLC, GC and SFC. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:309 / 363
页数:55
相关论文
共 383 条
[31]   Capillary electrophoretic separation of enantiomers using the single isomer heptakis-(2,3-dimethyl-6-sulfato)-β-cyclodextrin as chiral resolving agent in methanol-water background electrolytes [J].
Cai, H ;
Vigh, G .
JOURNAL OF CHROMATOGRAPHY A, 1998, 827 (01) :121-132
[32]   A family of single-isomer chiral resolving agents for capillary electrophoresis.: 3.: Heptakis(2,3-dimethyl-6-sulfato)-β-cyclodextrin [J].
Cai, H ;
Nguyen, TV ;
Vigh, G .
ANALYTICAL CHEMISTRY, 1998, 70 (03) :580-589
[33]  
Carlson R., 1992, Design and Optimization in Organic Synthesis
[34]   Enantiomeric separations by capillary electrochromatography using a macrocyclic antibiotic chiral stationary phase [J].
Carter-Finch, AS ;
Smith, NW .
JOURNAL OF CHROMATOGRAPHY A, 1999, 848 (1-2) :375-385
[35]   ISOLATION OF HUMAN SERUM TRANSFERRIN BY FREE-FLUID RECYCLING ELECTROPHORESIS IN SIMPLE BUFFERS [J].
CASLAVSKA, J ;
THORMANN, W .
ELECTROPHORESIS, 1994, 15 (8-9) :1176-1185
[36]   Determination of the enantiomeric purity of N-propionyl-6,7-dimethoxy-2-aminotetralin by cyclodextrin-modified micellar electrokinetic chromatography [J].
Castelnovo, P ;
Albanesi, C .
ELECTROPHORESIS, 1997, 18 (06) :996-1001
[37]   Study of the inclusion complexes of aromatic molecules with cyclodextrins using ionspray mass spectrometry [J].
Cescutti, P ;
Garozzo, D ;
Rizzo, R .
CARBOHYDRATE RESEARCH, 1996, 290 (02) :105-115
[38]   Recent trends in enantioseparations using capillary electromigration techniques [J].
Chankvetadze, B .
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1999, 18 (07) :485-498
[39]   Charged cyclodextrin derivatives as chiral selectors in capillary electrophoresis [J].
Chankvetadze, B ;
Endresz, G ;
Blaschke, G .
CHEMICAL SOCIETY REVIEWS, 1996, 25 (02) :141-&
[40]   Separation selectivity in chiral capillary electrophoresis with charged selectors [J].
Chankvetadze, B .
JOURNAL OF CHROMATOGRAPHY A, 1997, 792 (1-2) :269-295