Ultrasound-mediated interferon β gene transfection inhibits growth of malignant melanoma

被引：18
|
作者：
Yamaguchi, Kazuki [1 ,2 ]
Feril, Loreto B., Jr. [1 ]
Tachibana, Katsuro [1 ]
Takahashi, Akira [2 ]
Matsuo, Miki [2 ]
Endo, Hitomi [2 ]
Harada, Yoshimi [1 ]
Nakayama, Juichiro [2 ]
机构：
[1] Fukuoka Univ, Sch Med, Dept Anat, Jonan Ku, Fukuoka 8140180, Japan
[2] Fukuoka Univ, Sch Med, Dept Dermatol, Jonan Ku, Fukuoka 8140180, Japan
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2011年 / 411卷 / 01期
关键词：
Ultrasound; Sonotransfection; Melanoma; Interferon beta; PLASMID DNA; THERAPY; SONOPORATION; ENHANCEMENT; EXPRESSION; INDUCTION; EFFICIENT; DELIVERY; MUSCLE; CELLS;
D O I：
10.1016/j.bbrc.2011.06.115
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We investigated the effects of ultrasound-mediated transfection (sonotransfection) of interferon beta (IFN-beta) gene on melanoma (C32) both in vitro and in vivo. C32 cells were sonotransfected with IFN-beta in vitro. Subcutaneous C32 tumors in mice were sonicated weekly immediately after intra-tumor injection with IFN-beta genes mixed with microbubbles. Successful sonotransfection with IFN-beta gene in vitro was confirmed by ELISA, which resulted in C32 growth inhibition. In vivo, the growth ratio of tumors transfected with IFN-beta gene was significantly lower than the other experimental groups. These results may lead to a new method of treatment against melanoma and other hard-to-treat cancers. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码：137 / 142
页数：6
相关论文
共 50 条
  • [31] Optimising ultrasound-mediated gene transfer (sonoporation) in vitro and prolonged expression of a transgene in vivo: Potential applications for gene therapy of cancer
    Li, Ying Suet
    Davidson, Emma
    Reid, Cherith N.
    McHale, Anthony P.
    CANCER LETTERS, 2009, 273 (01) : 62 - 69
  • [32] Ultrasound-mediated microbubble delivery of pigment epithelium-derived factor gene into retina inhibits choroidal neovascularization
    Zhou Xi-yuan
    Liao Qing
    Pu Yi-min
    Tang Yong-qiang
    Gong Xiao
    Li Jia
    Xu Yan
    Wang Zhi-gang
    CHINESE MEDICAL JOURNAL, 2009, 122 (22) : 2711 - 2717
  • [33] Ultrasound-mediated gene transfer into neuronal cells
    Fischer, AJ
    Stanke, JJ
    Omar, G
    Askwith, CC
    Burry, RW
    JOURNAL OF BIOTECHNOLOGY, 2006, 122 (04) : 393 - 411
  • [34] Ultrasound-Mediated Vascular Gene Transfection by Cavitation of Endothelial-Targeted Cationic Microbubbles
    Xie, Aris
    Belcik, Todd
    Qi, Yue
    Morgan, Terry K.
    Champaneri, Shivam A.
    Taylor, Sarah
    Davidson, Brian P.
    Zhao, Yan
    Klibanov, Alexander L.
    Kuliszewski, Michael A.
    Leong-Poi, Howard
    Ammi, Azzdine
    Lindner, Jonathan R.
    JACC-CARDIOVASCULAR IMAGING, 2012, 5 (12) : 1253 - 1262
  • [35] Enhancing effect of ultrasound-mediated microbubble destruction on gene delivery into rat kidney via different administration routes
    Chen, Jun-Xiang
    Ma, Qiang
    Wu, Hong
    Zhou, An
    Chen, Xing
    Peng, You-Ming
    Liu, Fu-You
    Cheng, Mei-Chu
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2012, 5 (07) : 561 - 565
  • [36] Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites
    Ilovitsh, Tali
    Feng, Yi
    Foiret, Josquin
    Kheirolomoom, Azadeh
    Zhang, Hua
    Ingham, Elizabeth S.
    Ilovitsh, Asaf
    Tumbale, Spencer K.
    Fite, Brett Z.
    Wu, Bo
    Raie, Marina N.
    Zhang, Nisi
    Kare, Aris J.
    Chavez, Michael
    Qi, Lei S.
    Pelled, Gadi
    Gazit, Dan
    Vermesh, Ophir
    Steinberg, Idan
    Gambhir, Sanjiv S.
    Ferrara, Katherine W.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (23) : 12674 - 12685
  • [37] Ultrasound-responsive nanobubble-mediated gene transfection in the cerebroventricular region by intracerebroventricular administration in mice
    Ogawa, Koki
    Fuchigami, Yuki
    Hagimori, Masayori
    Fumoto, Shintaro
    Maruyama, Kazuo
    Kawakami, Shigeru
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2019, 137 : 1 - 8
  • [38] Effect of ultrasonic irradiation intensity on EGFP gene transfection and expression in tissue between bone defects in rabbits by ultrasound-mediated microbubble destruction
    Li, Shiwei
    Xie, Xiaoli
    Tang, Xueyang
    Liu, Lijun
    Liu, Fang
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 12 (04): : 3214 - 3225
  • [39] Influence of polymer adjuvants on the ultrasound-mediated transfection of cells in culture
    Mehier-Humbert, Sophie
    Bettinger, Thierry
    Yan, Feng
    Guy, Richard
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2009, 72 (03) : 567 - 573
  • [40] Low-intensity ultrasound inhibits melanoma cell proliferation in vitro and tumor growth in vivo
    Feril, Loreto B., Jr.
    Yamaguchi, Kazuki
    Ikeda-Dantsuji, Yurika
    Furusawa, Yukihiro
    Tabuchi, Yoshiaki
    Takasaki, Ichiro
    Ogawa, Ryohei
    Cui, Zheng-Guo
    Tachibana, Katsuro
    JOURNAL OF MEDICAL ULTRASONICS, 2021, 48 (04) : 451 - 461
12345