A stereodivergent synthesis of 3,4-disubstituted-2-azetidinones

被引：13

作者：

Collis, MP ^{[1
]}

Perlmutter, P ^{[1
]}

机构：

[1] MONASH UNIV,DEPT CHEM,CLAYTON,VIC 3168,AUSTRALIA

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 07期

关键词：

D O I：

10.1016/0957-4166(96)00255-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of a new aminolactone 1, using a highly diastereoselective conjugate addition of benzylamine to the unsaturated lactone 6 derived from D-mannitol, is described. The enantiospecific transformation of this aminolactone into either cis- or trans-3,4-disubstituted azetidinones, beta-amino esters as well as some aldol reactions are described. Copyright (C) 1996 Elsevier Science Ltd

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页码：2117 / 2134

页数：18

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