HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998

被引：453
作者：
Sacktor, N
Lyles, RH
Skolasky, R
Kleeberger, C
Selnes, OA
Miller, EN
Becker, JT
Cohen, B
McArthur, JC
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
[3] Univ Calif Los Angeles, Inst Neuropsychiat, Los Angeles, CA 90024 USA
[4] Univ Pittsburgh, Med Ctr, Neuropsychol Res Program, Pittsburgh, PA USA
[5] Northwestern Univ, Sch Med, Dept Neurol, Chicago, IL 60611 USA
来源：
NEUROLOGY | 2001年 / 56卷 / 02期
关键词：
D O I：
10.1212/WNL.56.2.257
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
This study examined the temporal trends in the incidence rates of HIV dementia, cryptococcal meningitis, toxoplasmosis, progressive multifocal leukoencephalopathy, and CNS lymphoma from January 1990 to December 1998 in the Multicenter AIDS Cohort Study. The incidence rates for HIV dementia, cryptococcal meningitis, and lymphoma decreased following the introduction of highly active antiretroviral therapy (HAART). The proportion of new cases of HIV dementia with a CD4 count in a higher range (i.e., 201 to 350) since 1996 may be increasing.
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页码：257 / 260
页数：4
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