Response to trabectedin treatment in a highly pretreated patient with an advanced meningeal hemangiopericytoma

被引：9

作者：

Martinez-Trufero, Javier ^{[1
]}

Alfaro, Jorge ^{[2
]}

Felipo, Francesc ^{[2
]}

Alvarez, Maria ^{[1
]}

Madani, Julia ^{[1
]}

Cebollero, Ana ^{[1
]}

机构：

[1] Hosp Univ Miguel Servet, Dept Med Oncol, Zaragoza 50009, Spain

[2] Hosp Univ Miguel Servet, Dept Pathol, Zaragoza 50009, Spain

来源：

ANTI-CANCER DRUGS | 2010年 / 21卷 / 08期

关键词：

hemangiopericytoma; rare tumor; solitary fibrous tumor; trabectedin; SOFT-TISSUE SARCOMA; CENTRAL-NERVOUS-SYSTEM; MALIGNANT HEMANGIOPERICYTOMA; PHASE-II; FIBROUS TUMOR; ECTEINASCIDIN-743; CHEMOTHERAPY; RADIOTHERAPY; EXPERIENCE; SUNITINIB;

D O I：

10.1097/CAD.0b013e32833d19f0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Meningeal hemangiopericytoma is an uncommon and aggressive malignancy that, in contrast to meningiomas, shows a high propensity for local recurrence and the development of late extraneural metastases. The results of chemotherapy in advanced hemangiopericytoma have been disappointing, and they have been particularly poor in cases located in the meninges. We report a case of a heavily pretreated metastatic meningeal hemangiopericytoma in which fourth-line chemotherapy with trabectedin, a marine-derived antineoplastic agent effective in treating advanced soft tissue sarcomas, resulted in clinical benefit. Anti-Cancer Drugs 21: 795-798 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

引用

页码：795 / 798

页数：4

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