Bronsted acidic ionic liquid catalyzed an eco-friendly and efficient procedure for synthesis of 2,4,5-trisubstituted imidazole derivatives under ultrasound irradiation and optimal conditions

被引:15
作者
Hilal, D. A. [1 ]
Hanoon, H. D. [1 ]
机构
[1] Univ Kerbala, Dept Chem, Coll Sci, Kerbala, Iraq
关键词
Benzil; Aldehydes; Ionic liquid; 2,4,5-Trisubstituted imidazole; Ultrasound irradiation; ONE-POT SYNTHESIS; GREEN; SILICA; 2,4,5-TRIARYL-1H-IMIDAZOLES; OXIDATION; REMOVAL; BENZIL; CARBON;
D O I
10.1007/s11164-019-04048-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
2-[(1H-imidazol-3-ium-3-yl)methyl]-4-{bis[3-((1H-imidazol-3-ium-3-yl) methyl-(4-hydroxyphenyl]methylene}cyclohexa-2,5-dienone trihydrogen sulfate ([2-(imm)-4-{b(immh)m}c][HSO4](3)), as the new Bronsted acidic ionic liquid, is effectively prepared and revealed by using FTIR, H-1 NMR, SEM, EDS, XRD and mass data. Afterward, its catalytic activity was investigated for the synthesis of 2,4,5-trisubstituted imidazole derivatives via the simple reaction between different aldehydes, ammonium acetate and benzil/benzoin under ultrasound irradiation at ambient temperature and optimal conditions. The novel procedure has the advantages of high yields, easy handling, short reaction times, and being eco-friendly and economical. Moreover, the catalyst can be easily recovered for several times without any additional treatment. [GRAPHICS] .
引用
收藏
页码:1521 / 1538
页数:18
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