Manipulation of host membrane machinery by bacterial pathogens

被引:64
作者
Cossart, Pascale [1 ,2 ,3 ]
Roy, Craig R. [4 ]
机构
[1] Inst Pasteur, Unite Interact Bacteries Cellules, F-75015 Paris, France
[2] INSERM, U604, F-75015 Paris, France
[3] INRA, USC2020, F-75015 Paris, France
[4] Yale Univ, Sch Med, Sect Microbial Pathogenesis, New Haven, CT 06536 USA
关键词
LISTERIA-MONOCYTOGENES; LEGIONELLA-PNEUMOPHILA; NUCLEOTIDE EXCHANGE; LIPID RAFTS; ESCHERICHIA-COLI; E-CADHERIN; ENTRY; ACTIN; MECHANISM; AUTOPHAGY;
D O I
10.1016/j.ceb.2010.05.006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Subversion of host membrane machinery is important for the uptake, survival, and replication of bacterial pathogens. Understanding how pathogens manipulate host membrane transport pathways provides mechanistic insight into how infection occurs and is also revealing new information on biochemical processes involved in the functioning of eukaryotic cells. In this review we discuss several of the canonical host pathways targeted by bacterial pathogens and emerging areas of investigation in this exciting field.
引用
收藏
页码:547 / 554
页数:8
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