Idiopathic constipation: A challenging but manageable problem

被引:19
作者
Bischoff, Andrea [1 ]
Brisighelli, Giulia [2 ]
Dickie, Belinda [3 ]
Frischer, Jason [4 ]
Levitt, Marc A. [5 ]
Pena, Alberto [1 ]
机构
[1] Childrens Hosp Colorado, Int Ctr Colorectal & Urogenital Care, 13123 East 16th Ave,Box 323,Anschutz Med Campus, Aurora, CO 80045 USA
[2] Fdn IRCCS CaGranda, Osped Maggiore Policlin, Milan, Italy
[3] Boston Childrens Hosp, Colorectal & Complex Pelvic Malformat Ctr, Boston, MA USA
[4] Cincinnati Childrens Hosp Med Ctr, Colorectal Ctr Children, Cincinnati, OH 45229 USA
[5] Nationwide Childrens Hosp, Ctr Colorectal & Pelvic Reconstruct, Columbus, OH USA
关键词
Idiopathic constipation; Encopresis; Laxative; Senna; Bowel management; ELECTRICAL-STIMULATION; CHILDREN; INCONTINENCE; ENEMAS;
D O I
10.1016/j.jpedsurg.2017.09.022
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose: A protocol to treat idiopathic constipation is presented. Methods: A contrast enema is performed in every patient and, when indicated, patients are initially submitted to a "clean out" protocol. All patients are started on a Senna-based laxative. The initial dosage is empirically determined and adjusted daily, during a one week period, based on history and abdominal radiographs, until the amount of Senna that empties the colon is reached. The management is considered successful when patients empty their colon daily and stop soiling. If the laxatives dose provokes abdominal cramping, distension, and vomiting, without producing bowel movements, patients are considered nonmanageable. Results: From 2005 to 2012, 215 patients were treated. 121 (56%) were males. The average age was 8.2 years (range: 1-20). 160 patients (74%) presented encopresis. 67 patients (32%) needed a clean out. After one week, 181 patients (84%) achieved successful management, with an average Senna dose of 67 mg (range: 5-175 mg). In 34 patients (16%) the treatment was unsuccessful: 19 were nonmanageable, 3 noncompliant, and 12 continued soiling. At a later follow-up (median: 329 days) the success rate for 174 patients was 81%. Conclusion: We designed a successful protocol to manage idiopathic constipation. The key points are clean out before starting laxatives, individual adjustments of laxative, and radiological monitoring of colonic emptying. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:1742 / 1747
页数:6
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