Total synthesis of pulverolide: revision of its structure

被引：19

作者：

Yang, Wanqiu ^{[1
,2
]}

Liu, Jikai ^{[1
,2
]}

Zhang, Hongbin ^{[3
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

[3] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Yunnan, Peoples R China

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 37期

关键词：

Pulverolide; Butenolide; Total synthesis; Revision of structure; PULVEROBOLETUS-RAVENELII; TRICHOLOMA-AURANTIUM; AGARICALES;

D O I：

10.1016/j.tetlet.2010.07.044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A flexible and practical strategy toward the synthesis of rare 2H-furo[3,2-b]benzopyran-2-one skeleton has been developed. With a microwave-assisted cyclization-dehydration as the key transformation, the first total synthesis of pulverolide has been completed in 10 steps with 9% overall yield, leading to the revision of its proposed structure. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：4874 / 4876

页数：3

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