An Energy-Efficient, Adiabatic Electrode Stimulator With Inductive Energy Recycling and Feedback Current Regulation

被引:87
作者
Arfin, Scott K. [1 ]
Sarpeshkar, Rahul [1 ]
机构
[1] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
基金
美国国家卫生研究院;
关键词
Charge recycling current source; dynamic power supply; electrode; energy recycling; implants; low power; neural stimulator; WIRELESS NEURAL STIMULATION; IMPLANTABLE STIMULATOR; VOLTAGE; INTERFACE; CIRCUIT; TISSUE; SAFE; CHIP;
D O I
10.1109/TBCAS.2011.2166072
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this paper, we present a novel energy-efficient electrode stimulator. Our stimulator uses inductive storage and recycling of energy in a dynamic power supply. This supply drives an electrode in an adiabatic fashion such that energy consumption is minimized. It also utilizes a shunt current-sensor to monitor and regulate the current through the electrode via feedback, thus enabling flexible and safe stimulation. Since there are no explicit current sources or current limiters, wasteful energy dissipation across such elements is naturally avoided. The dynamic power supply allows efficient transfer of energy both to and from the electrode and is based on a DC-DC converter topology that we use in a bidirectional fashion in forward-buck or reverse-boost modes. In an exemplary electrode implementation intended for neural stimulation, we show how the stimulator combines the efficiency of voltage control and the safety and accuracy of current control in a single low-power integrated-circuit built in a standard .35 mu m CMOS process. This stimulator achieves a 2x-3x reduction in energy consumption as compared to a conventional current-source-based stimulator operating from a fixed power supply. We perform a theoretical analysis of the energy efficiency that is in accord with experimental measurements. This theoretical analysis reveals that further improvements in energy efficiency may be achievable with better implementations in the future. Our electrode stimulator could be widely useful for neural, cardiac, retinal, cochlear, muscular and other biomedical implants where low power operation is important.
引用
收藏
页码:1 / 14
页数:14
相关论文
共 31 条
[1]   Wireless Neural Stimulation in Freely Behaving Small Animals [J].
Arfin, Scott K. ;
Long, Michael A. ;
Fee, Michale S. ;
Sarpeshkar, Rahul .
JOURNAL OF NEUROPHYSIOLOGY, 2009, 102 (01) :598-605
[2]   Millisecond-timescale, genetically targeted optical control of neural activity [J].
Boyden, ES ;
Zhang, F ;
Bamberg, E ;
Nagel, G ;
Deisseroth, K .
NATURE NEUROSCIENCE, 2005, 8 (09) :1263-1268
[3]   Development of a circuit for functional electrical stimulation [J].
Cheng, KWE ;
Lu, Y ;
Tong, KY ;
Rad, AB ;
Chow, DHK ;
Sutanto, D .
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 2004, 12 (01) :43-47
[4]   Neural stimulation and recording electrodes [J].
Cogan, Stuart F. .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2008, 10 :275-309
[5]   Deep brain stimulation for movement disorders [J].
Collins, Kelly L. ;
Lehmann, Emily M. ;
Patil, Parag G. .
NEUROBIOLOGY OF DISEASE, 2010, 38 (03) :338-345
[6]  
DBS 3387, 2008, DBS 3387 3389 LEAD K
[7]   A modular 32-site wireless neural stimulation microsystem [J].
Ghovanloo, M ;
Najafi, K .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 2004, 39 (12) :2457-2466
[8]   A compact large voltage-compliance high output-impedance programmable current source for implantable microstimulators [J].
Ghovanloo, M ;
Najafi, K .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2005, 52 (01) :97-105
[9]   A Power-Efficient Neural Tissue Stimulator With Energy Recovery [J].
Kelly, Shawn K. ;
Wyatt, John L., Jr. .
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2011, 5 (01) :20-29
[10]   A 64 Channel Programmable Closed-Loop Neurostimulator With 8 Channel Neural Amplifier and Logarithmic ADC [J].
Lee, Jongwoo ;
Rhew, Hyo-Gyuem ;
Kipke, Daryl R. ;
Flynn, Michael P. .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 2010, 45 (09) :1935-1945