Solubility Measurement of Diclofenac Acid in the Supercritical CO2

被引：49

作者：

Hezave, Ali Zeinolabedini ^{[1
]}

Esmaeilzadeh, Feridun ^{[1
]}

机构：

[1] Shiraz Univ, Sch Chem & Petr Engn, Shiraz 713451719, Iran

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2012年 / 57卷 / 06期

关键词：

POLYCYCLIC AROMATIC-HYDROCARBONS; DENSITY-BASED MODELS; CARBON-DIOXIDE; PHASE-EQUILIBRIA; SOLIDS; PHENANTHRENE; EXTRACTION; PRESSURE; LIQUIDS; ESTERS;

D O I：

10.1021/je200012x

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The equilibrium solubility of the diclofenac acid in supercritical carbon dioxide was determined with a static method. The measurements were performed at pressures ranging from (120 to 400) bar and temperatures from (308.15 to 338.15) K. The results show that diclofenac acid solubility was increased by increasing pressure. The experimental solubility data were well correlated with enhanced density-based models including the Chrastil model, Mendez-Santiago and Teja model, Kumar and Johnston model, and the Bartle and co-workers model with an average absolute relative deviation (AARD) of 8.7 %, 6.6 %, 7.2 %, and 9.7 %, respectively. In addition, the solubility data satisfied the self-consistency test, proposed by Mendez-Santiago and Teja.

引用

页码：1659 / 1664

页数：6

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