Cross-Reactivity of Fusarium spp. in the Aspergillus Galactomannan Enzyme-Linked Immunosorbent Assay

被引：137

作者：

Tortorano, Anna Maria ^{[1
]}

Esposto, Maria Carmela ^{[1
]}

Prigitano, Anna ^{[1
]}

Grancini, Anna ^{[2
]}

Ossi, Cristina ^{[3
]}

Cavanna, Caterina ^{[4
]}

Lo Cascio, Giuliana ^{[5
]}

机构：

[1] Univ Milan, Dipartimento Sanita Pubbl Microbiol Virol, I-20122 Milan, Italy

[2] Fdn IRCCS Osped Maggiore Policlin, Microbiol Lab, Milan, Italy

[3] IRCCS Osped San Raffaele, LabRaf, Milan, Italy

[4] IRCCS Osped San Matteo, Pavia, Italy

[5] Azienda Osped Verona, Microbiol Serv, Verona, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 03期

关键词：

INVASIVE ASPERGILLOSIS; INFECTIONS; IMMUNOASSAY; ANTIGEN; DISEASE;

D O I：

10.1128/JCM.05946-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Nine of 11 hematological patients with disseminated/deep-seated Fusarium infection tested at least twice for Aspergillus galactomannan (GM) had repeated positive results in the absence of Aspergillus isolation in culture. The centrifuged supernatants of 12 Fusarium isolates were tested by a GM enzyme-linked immunosorbent assay (EIA). All the isolates produced positive reactions when tested undiluted. These results show cross-reactivity of Fusarium spp. with Aspergillus GM that may constitute a drawback with respect to the specificity of the Platelia EIA.

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收藏

页码：1051 / 1053

页数：3

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