Upper-body morbidity after breast cancer

被引:272
作者
Hayes, Sandra C. [1 ]
Johansson, Karin [2 ]
Stout, Nicole L. [3 ]
Prosnitz, Robert [4 ]
Armer, Jane M. [5 ]
Gabram, Sheryl [6 ]
Schmitz, Kathryn H. [7 ]
机构
[1] Queensland Univ Technol, Sch Publ Hlth, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia
[2] Univ Lund Hosp, Dept Oncol, S-22185 Lund, Sweden
[3] Walter Reed Natl Mil Med Ctr, Breast Care Ctr, Bethesda, MD USA
[4] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA
[5] Univ Missouri, Sinclair Sch Nursing, Columbia, MO USA
[6] Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA
[7] Univ Penn, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA
关键词
breast cancer; upper-body morbidity; lymphedema; incidence; prevention; treatment; QUALITY-OF-LIFE; LYMPH-NODE BIOPSY; RANDOMIZED CONTROLLED-TRIAL; UPPER-LIMB MORBIDITY; LEVEL LASER THERAPY; ARM LYMPHEDEMA; AXILLARY DISSECTION; FOLLOW-UP; POSTMASTECTOMY LYMPHEDEMA; RISK-FACTORS;
D O I
10.1002/cncr.27467
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The purpose of this paper is to review the incidence of upper-body morbidity (arm and breast symptoms, impairments, and lymphedema), methods for diagnosis, and prevention and treatment strategies. It was also the purpose to highlight the evidence base for integration of prospective surveillance for upper-body morbidity within standard clinical care of women with breast cancer. Between 10% and 64% of women report upper-body symptoms between 6 months and 3 years after breast cancer, and approximately 20% develop lymphedema. Symptoms remain common into longer-term survivorship, and although lymphedema may be transient for some, those who present with mild lymphedema are at increased risk of developing moderate to severe lymphedema. The etiology of morbidity seems to be multifactorial, with the most consistent risk factors being those associated with extent of treatment. However, known risk factors cannot reliably distinguish between those who will and will not develop upper-body morbidity. Upper-body morbidity may be treatable with physical therapy. There is also evidence in support of integrating regular surveillance for upper-body morbidity into the routine care provided to women with breast cancer, with early diagnosis potentially contributing to more effective management and prevention of progression of these conditions. Cancer 2012;118(8 suppl). (c) 2012 American Cancer Society.
引用
收藏
页码:2237 / 2249
页数:13
相关论文
共 158 条
[1]  
Agency for Healthcare Research and Quality, TECHN ASS DIAGN TREA
[2]   Randomized controlled trial of weight training and lymphedema in breast cancer survivors [J].
Ahmed, Rehana L. ;
Thomas, William ;
Yee, Douglas ;
Schmitz, Kathryn H. .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (18) :2765-2772
[3]   Early self-reported impairments in arm functioning of primary breast cancer patients predict late side effects of axillary lymph node dissection: results from a population-based cohort study [J].
Albert, Ute S. ;
Koller, Michael ;
Kopp, Ina ;
Lorenz, Wilfried ;
Schulz, Klaus D. ;
Wagner, Uwe .
BREAST CANCER RESEARCH AND TREATMENT, 2006, 100 (03) :285-292
[4]   PATHOPHYSIOLOGY OF IRRADIATED SKIN AND BREAST [J].
ARCHAMBEAU, JO ;
PEZNER, R ;
WASSERMAN, T .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1995, 31 (05) :1171-1185
[5]  
Armer JM, 2010, LYMPHOLOGY, V43, P118
[6]  
Armer Jane M., 2005, Lymphatic Research and Biology, V3, P208, DOI 10.1089/lrb.2005.3.208
[7]   Predicting breast cancer-related lymphedema using self-reported symptoms [J].
Armer, JM ;
Radina, ME ;
Porock, D ;
Culbertson, SD .
NURSING RESEARCH, 2003, 52 (06) :370-379
[8]   A population-based study of the impact of specific symptoms on quality of life in women with breast cancer 1 year after diagnosis [J].
Arndt, Volker ;
Stegmaier, Christa ;
Ziegler, Hartwig ;
Brenner, Hermann .
CANCER, 2006, 107 (10) :2496-2503
[9]   Risk factors for developing upper limb lymphedema after breast cancer treatment [J].
Arrault, Maria ;
Vignes, Stephane .
BULLETIN DU CANCER, 2006, 93 (10) :1001-1006
[10]  
Badger C, 2003, COCHRANE DB SYST REV, DOI DOI 10.1002/14651858.CD003140.PUB2