Digital Light 3D Printing of PEDOT-Based Photopolymerizable Inks for Biosensing

被引：52

作者：

Lopez-Larrea, Naroa ^{[1
]}

Criado-Gonzalez, Miryam ^{[1
]}

Dominguez-Alfaro, Antonio ^{[1
]}

Alegret, Nuria ^{[2
,3
]}

del Agua, Isabel ^{[4
]}

Marchiori, Bastien ^{[4
]}

Mecerreyes, David ^{[1
,5
]}

机构：

[1] Univ Basque Country UPV, POLYMAT, EHU, San Sebastian 20018, Spain

[2] Ctr Cooperat Res Biomat CIC biomaGUNE, Carbon Bionanotechnol Grp, Basque Res & Technol Alliance BRTA, San Sebastian 20014, Spain

[3] Grp Neuromuscular Dis, IIS Biodonostia, Neurosci Area, Paseo Dr Begiristain S-N, San Sebastian 20014, Spain

[4] Panaxium SAS, F-13100 Aix En Provence, France

[5] Basque Fdn Sci, Ikerbasque, Bilbao 48013, Spain

来源：

ACS APPLIED POLYMER MATERIALS | 2022年 / 4卷 / 09期

关键词：

conducting polymers; photopolymerizable inks; hydrogels; digital light printing; biosensing; ETHYLENE-GLYCOL; HYDROGEL; ELECTROPHYSIOLOGY; WATER;

D O I：

10.1021/acsapm.2c01170

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

3D conductive materials such as polymers and hydrogels that interface between biology and electronics are actively being researched for the fabrication of bioelectronic devices. In this work, short-time (5 s) photopolymerizable conductive inks based on poly(3,4-ethylenedioxythiophene) (PEDOT):polystyrene sulfonate (PSS) dispersed in an aqueous matrix formed by a vinyl resin, poly(ethylene glycol) diacrylate (PEGDA) with different molecular weights (M-n = 250, 575, and 700 Da), ethylene glycol (EG), and a photoinitiator have been optimized. These inks can be processed by Digital Light 3D Printing (DLP) leading to flexible and shape-defined conductive hydrogels and dry conductive PEDOTs, whose printability resolution increases with PEGDA molecular weight. Besides, the printed conductive PEDOT-based hydrogels are able to swell in water, exhibiting soft mechanical properties (Young's modulus of similar to 3 MPa) similar to those of skin tissues and good conductivity values (10(-2) S cm(-1)) for biosensing. Finally, the printed conductive hydrogels were tested as bioelectrodes for human electrocardiography (ECG) and electromyography (EMG) recordings, showing a long-term activity, up to 2 weeks, and enhanced detection signals compared to commercial Ag/AgCl medical electrodes for health monitoring.

引用

页码：6749 / 6759

页数：11

共 55 条

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