Chemical site-selective prenylation of proteins

被引：23

作者：

Gamblin, David P. ^{[1
]}

van Kasteren, Sander ^{[1
]}

Bernardes, Goncalo J. L. ^{[1
]}

Chalker, Justin M. ^{[1
]}

Oldham, Neil J. ^{[1
,2
]}

Fairbanks, Antony J. ^{[1
]}

Davis, Benjamin G. ^{[1
]}

机构：

[1] Univ Oxford, Chem Res Lab, Dept Chem, Oxford OX1 3TA, England

[2] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

MOLECULAR BIOSYSTEMS | 2008年 / 4卷 / 06期

基金：

英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b802199f

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A direct thionation procedure allows conversion of allylic alcohols into the corresponding thiols, the products of which are immediately compatible with one-pot site-selective selenenyl sulfide mediated protein conjugation.

引用

页码：558 / 561

页数：4

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