Coronavirus disease 2019 and vaccination in patients with Shwachman-Diamond syndrome

被引：2

作者：

Galletta, Thomas J. ^{[1
]}

Loveless, Sara K. ^{[2
]}

Malsch, Maggie M. ^{[3
]}

Shimamura, Akiko ^{[4
,5
]}

Myers, Kasiani C. ^{[2
,6
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Cincinnati, OH 45229 USA

[2] Cincinnati Childrens Hosp Med Ctr, Div Bone Marrow Transplantat & Immune Deficiency, Cincinnati, OH 45229 USA

[3] Boston Childrens Hosp, Inst Ctr Clin & Translat Res, Boston, MA USA

[4] Dana Farber Boston Childrens Canc & Blood Disorde, Boston, MA USA

[5] Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA

[6] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

来源：

PEDIATRIC BLOOD & CANCER | 2022年 / 69卷 / 05期

关键词：

Bone marrow failure; COVID-19; general hematology; infections in immunocompromised hosts; infectious disease; vaccines; viral infection;

D O I：

10.1002/pbc.29647

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Because they can experience neutropenia due to bone marrow failure, patients with Shwachman-Diamond syndrome (SDS) carry increased risk for serious infections compared with the general population; however, there has been a paucity of data on the incidence and severity of coronavirus disease 2019 (COVID-19) in patients with SDS. We compiled results from a survey distributed to participants in the SDS Registry in May-June 2021. In this report, we describe the characteristics and outcomes of patients with SDS who had COVID-19. Patients reported a short clinical course without significant complications or cytopenias. Additionally, COVID-19 vaccines were well tolerated with minor side effects.

引用

页数：4