The limits of determination for anions in water with the capillary electrophoresis method

In the case of capillary electrophoresis the limits of determination xo cannot be defined according to the accepted definition. The paper presents the approach applied and recommended by EURACHEM, relying on the approximation of the graph representing the relationships between the relative standard deviation RSD (%) and the concentration of given indicator in the spiked sample. Consistent with this approach the limit of determination is the lowest concentration of analyte in the sample which can be exactly quantified with precision, determined by the level of RSD (%).