Intramolecular Friedel-Crafts Alkylation of Chalcone Epoxides Using Indium(III) Chloride as an Efficient Catalyst

被引：14

作者：

Ahmed, Naseem ^{[1
]}

Babu, B. Venkata ^{[1
]}

Kumar, Harendra ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Roorkee 247667, Uttarakhand, India

来源：

SYNTHESIS-STUTTGART | 2011年 / 15期

关键词：

indium(III) chloride; intramolecular Friedel-Crafts alkylation; chalcones epoxides; epoxide ring opening; 2,3-dihydro-1H-inden-1-ones; NAZAROV CYCLIZATION; CORRESPONDING 2-ARYL-2,3-DIHYDROQUINOLIN-4(1H)-ONES; ENANTIOSELECTIVE SYNTHESIS; REGIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; POLYPHOSPHORIC ACID; INDANONES; 1-INDANONES; ACYLATION; DERIVATIVES;

D O I：

10.1055/s-0030-1260091

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indium(III) chloride catalyzes the ring opening of chalcone epoxides followed by intramolecular Friedel-Crafts alkylation under mild conditions at room temperature to afford highly functionalized 3-aryl-2-hydroxy-2,3-dihydro-1H-inden-1-ones in excellent yields (81-95%).

引用

页码：2471 / 2477

页数：7

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