Proniosomes: the effective and efficient drug-carrier system

被引:19
作者
Mittal, Swati [1 ]
Chaudhary, Amit [1 ]
Chaudhary, Anjali [2 ]
Kumar, Ankit [3 ]
机构
[1] Abhilashi Univ, Sch Pharm, Mandi 175028, Himachal Prades, India
[2] Indian Pharmacopoeia Commiss, Ghaziabad 201002, Uttar Pradesh, India
[3] Swami Vivekanand Subharti Univ, Kharvel Subharti Coll Pharm, NH 58, Meerut 250005, Uttar Pradesh, India
关键词
mechanism; nonionic; particle size; proniosomes; skin permeation; surfactant; targeting; topical; transdermal; vesicles; TRANSDERMAL DELIVERY; IN-VITRO; POTENTIAL TREATMENT; NIOSOMES; OPTIMIZATION; TACROLIMUS; VESICLES; ACID; GEL; ETHOSOMES(R);
D O I
10.4155/tde-2019-0065
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Niosomes, liposomes and proniosomes are the most abundantly used vesicular systems for the transdermal delivery of drugs. Proniosomes are nonhydrated niosomes, which, upon hydration, form niosomes. Various researches have proved the advantages of proniosomes over the other conventional dosage forms currently available in the market. Proniosomes overcome physical stability problems involved with other vesicular systems such as leaking, fusion and aggregation. The stability and shelf life of proniosomes especially have been found to be much better and prolonged in comparison to other vesicular systems such as liposomes. The present review has been written in an effort to bring yet another viewpoint from a different angle and curated to compile the latest updates in this highly attractive delivery system from today's research point.
引用
收藏
页码:125 / 137
页数:13
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