Preparation of voltammetric biosensor for tryptophan using multi-walled carbon nanotubes

被引：19

作者：

Kia, Majid ^{[1
]}

Islamnezhad, Akbar ^{[1
]}

Shariati, Shahab ^{[1
]}

Biparva, Pouria ^{[2
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Fac Sci, Rasht, Iran

[2] Iranian Acad Ctr Educ Culture & Res ACECR, Res Dept Chromatog, Urmia Branch, Orumiyeh, Iran

来源：

KOREAN JOURNAL OF CHEMICAL ENGINEERING | 2011年 / 28卷 / 10期

关键词：

Biosensor; Cyclic Voltammetry; Multi-walled Carbon Nanotubes; Chemical Vapor Deposition; Electrocatalytic Effect; PERFORMANCE LIQUID-CHROMATOGRAPHY; PASTE ELECTRODE; CAPILLARY-ELECTROPHORESIS; AMPEROMETRIC DETERMINATION; ELECTROCHEMICAL DETECTION; EXCHANGE CHROMATOGRAPHY; ACID COMPLEXES; AMINO-ACIDS; BEHAVIOR; TYROSINE;

D O I：

10.1007/s11814-011-0066-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multi-walled carbon nanotubes (MWCNTs) were grown by chemical vapor deposition. The effect of the composition of carbon paste electrode on its voltammograms was evaluated in basic solution with 5.0x10(-5) M tryptophan (Trp). It was found that addition of MWCNTs to the carbon paste would generate the peak current of Trp because of its catalytic effect on the redox process. The pH strongly affects the peak potential of Trp. The best analytical response was obtained at pH 13.0. The anodic peak currents were proportional to Trp concentrations in the range of 1.0x10(-9)-1.0x10(-4) M under the optimized experimental conditions. The detection limit was 2.2x10(-10) M. The effect of potential scan rate on the peak potential and peak current of tryptophan was investigated. The correlation of the peak currents against v(1/2) (v is the scan rate) is linear, which is very similar to a diffusion-controlled process. The proposed biosensor was applied to the determination of Trp in pharmaceuticals formulations successfully.

引用

页码：2064 / 2068

页数：5

共 42 条

[1] Flow injection potentiometric determination of amantadine HCl [J].