Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

被引：108

作者：

Hartman, R. ^{[1
]}

Helmy, R. ^{[1
]}

Al-Sayah, M. ^{[1
]}

Welch, Christopher J. ^{[1
]}

机构：

[1] Early Dev Analyt Res Merck & Co, Rahway, NJ 07065 USA

来源：

GREEN CHEMISTRY | 2011年 / 13卷 / 04期

关键词：

ORGANIC-SYNTHESIS; CATALYSIS; FUTURE;

D O I：

10.1039/c0gc00524j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Analytical Method Volume Intensity (AMVI), a simple metric developed to measure the total solvent consumption of an HPLC method, can help chemists make informed decisions on how to lower an analytical method's environmental impact.

引用

页码：934 / 939

页数：6

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