From Lignin to Valuable Aromatic Chemicals: Lignin Depolymerization and Monomer Separation via Centrifugal Partition Chromatography

被引:82
作者
Alherech, Manar [1 ]
Omolabake, Surajudeen [1 ]
Holland, Christopher M. [1 ,2 ]
Klinger, Gracielou E. [3 ]
Hegg, Eric L. [3 ]
Stahl, Shannon S. [1 ,2 ]
机构
[1] Univ Wisconsin Madison, Dept Chem, Madison, WI 53706 USA
[2] Univ Wisconsin Madison, Wisconsin Energy Inst, Madison, WI 53726 USA
[3] Michigan State Univ, Dept Biochem & Mol Biol, E Lansing, MI 48824 USA
关键词
BIOMASS FRACTIONATION; VANILLIN; SYRINGALDEHYDE; OXIDATION; CONVERSION;
D O I
10.1021/acscentsci.1c00729
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lignin has long been recognized as a potential feedstock for aromatic molecules; however, most lignin depolymer-ization methods create a complex mixture of products. The present study describes an alkaline aerobic oxidation method that converts lignin extracted from poplar into a collection of oxygenated aromatics, including valuable commercial compounds such as vanillin and p-hydroxybenzoic acid. Centrifugal partition chroma-tography (CPC) is shown to be an effective method to isolate the individual compounds from the complex product mixture. The liquid-liquid extraction method proceeds in two stages. The crude depolymerization mixture is first subjected to ascending-mode extraction with the Arizona solvent system L (pentane/ethyl acetate/ methanol/water 2:3:2:3), enabling isolation of vanillin, syringic acid, and oligomers. The remaining components, syringaldehyde, vanillic acid, and p-hydroxybenzoic acid (pHBA), were resolved by using ascending-mode extraction with solvent mixture comprising dichloromethane/methanol/water (10:6:4) separation. These results showcase CPC as an effective technology that could provide scalable access to valuable chemicals from lignin and other biomass-derived feedstocks.
引用
收藏
页码:1831 / 1837
页数:7
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