Synthesis of new azo dye compounds derived from 2-aminobenzothiazole and study their biological activity

被引：6

作者：

Al-Joboury, Wissam M. R. ^{[1
]}

Al-Badrany, Khalid A. ^{[1
]}

Asli, Nabeel J. ^{[1
]}

机构：

[1] Tikrit Univ, Dept Chem, Coll Educ Pure Sci, Tikrit, Iraq

来源：

MATERIALS TODAY-PROCEEDINGS | 2021年 / 47卷

关键词：

Azo dyes; 2-Amino benzothiazoles; Poly acryloyl chloride; BENZOTHIAZOLE; COMPLEXES;

D O I：

10.1016/j.matpr.2021.04.538

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In this work, new 2-amino benzothiazole (W1) were synthesized from the reaction between aniline substituted with potassium thiocyanate in presence of broom. (W1) reaction with phenol substituted to give azo dyes compound (W2-W5). Polyacrylic acid was converted into poly acryloyl chloride by reaction poly acrylic acid with thionyl chloride was dissolved in acetonitrile with reaction different organic compounds. (W1-9) characterized were using (IR) and (HNMR-CNMR-CHN-TLC) techniques and the analysis revealed biological activity for chemical compounds at three concentrations (0.01, 0.001, 0.0001) mg/ml. (MIC) was calculated using standard drugs as a comparison. The findings revealed that azo derivatives outperformed medication in inhibiting the growth of gram negative & positive bacteria. (c) 2021 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the Technology Innovation in Mechanical Engineering-2021.

引用

页码：5977 / 5982

页数：6

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