Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers

被引：53

作者：

Edwards, Paul C. ^{[1
]}

Fantasia, John E. ^{[2
]}

机构：

[1] Univ Michigan, Sch Dent, Dept Periodont & Oral Med Pathol & Oncol, Ann Arbor, MI 48109 USA

[2] Long Isl Jewish Med Ctr, Dept Dent Med, Div Oral Pathol, New Hyde Pk, NY 11042 USA

来源：

CLINICAL INTERVENTIONS IN AGING | 2007年 / 2卷 / 04期

关键词：

hyaluronic acid; Restylane (R); Hylaform (R); injectable dermal filler; foreign body reaction; granuloma;

D O I：

10.2147/CIA.S382

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Although only recently introduced, chemically-modified hyaluronic acid dermal fillers have gained widespread acceptance as "redefining" dermal fillers in the fields of dermatology and cosmetic facial surgery. Although hyaluronic acid-based dermal fillers have a low overall incidence of long term side effects, occasional adverse outcomes, ranging from chronic lymphoplasmacytic inflammatory reactions to classic foreign body-type granulomatous reactions have been documented. These long-term adverse events are reviewed.

引用

页码：509 / 519

页数：11

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