Genetically Encoded Click Chemistry†

被引：21

作者：

Sun, Fei ^{[1
]}

Zhang, Wen-Bin ^{[2
]}

机构：

[1] Hong Kong Univ Sci & Technol, Dept Chem & Biol Engn, Kowloon, Clear Water Bay, Hong Kong, Peoples R China

[2] Peking Univ, Coll Chem & Mol Engn, Minist Educ,Ctr Soft Matter Sci & Engn, Beijing Natl Lab Mol Sci,Key Lab Polymer Chem & P, Beijing 100871, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2020年 / 38卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Click chemistry; SpyTag; SpyCatcher; Topology engineering; Synthetic biology; TOPOLOGY;

D O I：

10.1002/cjoc.202000101

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Genetically encoded click chemistry (GECC) refers to a category of peptide/protein reactions that can spontaneously form covalent linkages with high efficiency and selectivity under mild physiological conditions. The emergence of powerful SpyTag/SpyCatcher chemistry, a prototype of GECC, has opened the door to new fields such as in cellulo protein topology engineering and design of synthetic organelles. The continuing developments of GECC will surely provide great opportunities for future materials science and synthetic biology and open up a new avenue to information-coded chemical reactions.

引用

页码：894 / 896

页数：3

共 10 条

[1] Active Template Synthesis of Protein Heterocatenanes [J].

Da, Xiao-Di ;

Zhang, Wen-Bin .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (32) :11097-11104

[2] Programmable and printable Bacillus subtilis biofilms as engineered living materials [J].

Huang, Jiaofang ;

Liu, Suying ;

Zhang, Chen ;

Wang, Xinyu ;

Pu, Jiahua ;

Ba, Fang ;

Xue, Shuai ;

Ye, Haifeng ;

Zhao, Tianxin ;

Li, Ke ;

Wang, Yanyi ;

Zhang, Jicong ;

Wang, Lihua ;

Fan, Chunhai ;

Lu, Timothy K. ;

Zhong, Chao .

NATURE CHEMICAL BIOLOGY, 2019, 15 (01) :34-+

[3] Approaching infinite affinity through engineering of peptide-protein interaction [J].

Keeble, Anthony H. ;

Turkki, Paula ;

Stokes, Samuel ;

Anuar, Irsyad N. A. Khairil ;

Rahikainen, Rolle ;

Hytonen, Vesa P. ;

Howarth, Mark .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (52) :26523-26533

[4]

Kolb HC, 2001, ANGEW CHEM INT EDIT, V40, P2004, DOI 10.1002/1521-3773(20010601)40:11<2004::AID-ANIE2004>3.3.CO

[5]

2-X

[6] Topology Engineering of Proteins in Vivo Using Genetically Encoded, Mechanically Interlocking SpyX Modules for Enhanced Stability [J].

Liu, Dong ;

Wu, Wen-Hao ;

Liu, Ya-Jie ;

Wu, Xia-Ling ;

Cao, Yang ;

Song, Bo ;

Li, Xiaopeng ;

Zhang, Wen-Bin .

ACS CENTRAL SCIENCE, 2017, 3 (05) :473-481

[7] Self-Assembled Multienzyme Nanostructures on Synthetic Protein Scaffolds [J].

Liu, Zhenjun ;

Cao, Sheng ;

Liu, Miao ;

Kang, Wei ;

Xia, Jiang .

ACS NANO, 2019, 13 (10) :11343-11352

[8] Dynamically Tunable, Macroscopic Molecular Networks Enabled by Cellular Synthesis of 4-Arm Star-like Proteins [J].

Yang, Zhongguang ;

Yang, Yang ;

Wang, Mo ;

Wang, Tingting ;

Fok, Hong Kiu Francis ;

Jiang, Bojing ;

Xiao, Wendi ;

Kou, Songzi ;

Guo, Yusong ;

Yan, Yan ;

Deng, Xin ;

Zhang, Wen-Bin ;

Sun, Fei .

MATTER, 2020, 2 (01) :233-249

[9] Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin [J].

Zakeri, Bijan ;

Fierer, Jacob O. ;

Celik, Emrah ;

Chittock, Emily C. ;

Schwarz-Linek, Ulrich ;

Moy, Vincent T. ;

Howarth, Mark .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (12) :E690-E697

[10] Controlling Macromolecular Topology with Genetically Encoded SpyTag-SpyCatcher Chemistry [J].

Zhang, Wen-Bin ;

Sun, Fei ;

Tirrell, David A. ;

Arnold, Frances H. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (37) :13988-13997

← 1 →