A novel dual chemosensor for selective heavy metal ions Al3+, Cr3+ and its applicable cytotoxic activity, HepG2 living cell images and theoretical studies

被引：23
作者：
Dhineshkumar, Ezhumalai [1 ]
Iyappan, Mathivanan [1 ]
Anbuselvan, Chinnadurai [1 ,2 ]
机构：
[1] Annamalai Univ, Dept Chem, Annamalainagar 608002, Tamil Nadu, India
[2] Govt Arts Coll Chidambaram, PG & Res Dept Chem, Chidambaram 608102, India
来源：
JOURNAL OF MOLECULAR STRUCTURE | 2020年 / 1210卷
关键词：
Schiff base; Al3+/Cr3+; Colorimetric; Live cells and DFT; FLUORESCENCE TURN-ON; ALUMINUM ACCUMULATION; COLORIMETRIC SENSORS; MOLECULAR PROBE; FT-IR; CHROMIUM; FE3+; ZN2+; HYPERPOLARIZABILITIES; ENVIRONMENT;
D O I：
10.1016/j.molstruc.2020.128033
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A new simple 'dual' chemosensor (3,3'-(1,3-phenylene)bis(quinoxaline-6,3-diyl))bis (phenylmethanone) L14, for distinguishing Al3+ and Cr3+ has been designed, synthesized and characterized. The designed compound revealed certified selectivity and sensitivity among a fluorescence enhancement to Al3+ and quenching to Cr3+ over commonly coexisting cations (such as Cu2+, Hg-2(+), Fe2+, Pb2+, Ag+, Ni2+, Zr2+, Mn2+, Mg2+, Sr-2(+), Sn2+, Bi3+ and Zn2+) in DMF-H2O (4/1, v/v). These are reversible with the addition of EDTA. The detection limit for Al3+ /Cr3+ by L14 reached the 0.3 mu M and 0.5 mu M level. The binding process confirmed via UV-Vis, fluorescence measurements, H-1 NMR, FE-SEM with EDS and color mapping and DFT calculation. Further, the applicability of the probe was used to the cytotoxic activity, and fluorescent sensors in overseeing intracellular Al3+/Cr3+ in HepG2 cells also demonstrated. (C) 2020 Elsevier B.V. All rights reserved.
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页数：12
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