New tendencies in non-surgical periodontal therapy

被引：44

作者：

Haas, Alex Nogueira ^{[1
]}

Furlaneto, Flavia ^{[2
]}

Gaio, Eduardo Jose ^{[1
]}

Gomes, Sabrina Carvalho ^{[1
]}

Palioto, Daniela Bazan ^{[2
]}

Castilho, Rogerio Moraes ^{[3
]}

Sanz, Mariano ^{[4
]}

Messora, Michel Reis ^{[2
]}

机构：

[1] Univ Fed Rio Grande do Sul UFRGS, Sch Dent, Dept Periodontol, Porto Alegre, RS, Brazil

[2] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Oral Surg & Periodontol, Ribeirao Preto, SP, Brazil

[3] Michigan Univ, Sch Dent, Dept Periodont & Oral Med, Ann Arbor, MI USA

[4] Univ Complutense Madrid, Etiol & Therapy Periodontal & Periimplant Dis Res, Madrid, Spain

来源：

BRAZILIAN ORAL RESEARCH | 2021年 / 35卷

关键词：

Fatty Acids; Omega-3; Periodontal Debridement; Probiotics; Ozone; Epigenomics; ANTIMICROBIAL PHOTODYNAMIC THERAPY; LACTOBACILLUS-BREVIS CD2; POLYUNSATURATED FATTY-ACIDS; DNA METHYLATION STATUS; LOCAL-DRUG DELIVERY; IL8 GENE PROMOTER; LETHAL PHOTOSENSITIZATION; PORPHYROMONAS-GINGIVALIS; ORAL BACTERIA; DOUBLE-BLIND;

D O I：

10.1590/1807-3107bor-2021.vol35.0095

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The aim of this review was to update the evidence of new approaches to non-surgical therapy (NSPT) in the treatment of periodontitis. Preclinical and clinical studies addressing the benefits of adjunctive antimicrobial photodynamic therapy, probiotics, prebiotics/synbiotics, statins, pro-resolving mediators, omega-6 and -3, ozone, and epigenetic therapy were scrutinized and discussed. Currently, the outcomes of these nine new approaches, when compared with subgingival debridement alone, did not demonstrate a significant added clinical benefit. However, some of these new alternative interventions may have the potential to improve the outcomes of NSPT alone. Future evidence based on randomized controlled clinical trials would help clinicians and patients in the selection of different adjunctive therapies.

引用

页码：1 / 18

页数：18

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