Operationalizing NIMH Research Domain Criteria (RDoC) in naturalistic clinical settings

被引：9

作者：

Sharp, Carla ^{[1
,2
]}

Fowler, J. Christopher ^{[2
,3
]}

Salas, Ramiro ^{[3
]}

Nielsen, David ^{[3
,4
]}

Allen, Jon ^{[2
,3
]}

Oldham, John ^{[2
,3
]}

Kosten, Thomas ^{[4
]}

Mathew, Sanjay ^{[2
,3
]}

Madan, Alok ^{[2
,3
]}

Frueh, B. Christopher ^{[2
,5
]}

Fonagy, Peter ^{[2
,6
]}

机构：

[1] Univ Houston, Dept Psychol, Houston, TX 77204 USA

[2] Menninger Clin, Houston, TX USA

[3] Baylor Coll Med, Houston, TX 77030 USA

[4] Michael E DeBakey VA Med Ctr, Houston, TX USA

[5] Univ Hawaii, Hilo, HI 96720 USA

[6] UCL, London, England

来源：

BULLETIN OF THE MENNINGER CLINIC | 2016年 / 80卷 / 03期

基金：

美国国家卫生研究院;

关键词：

COMMON MENTAL-DISORDERS; DSM-V; PREDICTION ERRORS; RESEARCH AGENDA; HUMAN STRIATUM; BRAIN-FUNCTION; CLASSIFICATION; REWARD; NEUROSCIENCE; PSYCHIATRY;

D O I：

10.1521/bumc.2016.80.3.187

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Recently, the National Institute of Mental Health (NIMH) introduced the Research Domain Criteria (RDoC) initiative to address two major challenges facing the field of psychiatry: (1) the lack of new effective personalized treatments for psychiatric disorders, and (2) the limitations associated with categorically defined psychiatric disorders. Although the potential of RDoC to revolutionize personalized psychiatric medicine and psychiatric nosology has been acknowledged, it is unclear how to implement RDoC in naturalistic clinical settings as part of routine outcomes research. In this article, the authors present the major RDoC principles and then show how these principles are operationalized in The Menninger Clinic's McNair Initiative for Neuroscience Discovery-Menninger & Baylor College of Medicine (MIND-MB) study. The authors discuss how RDoC-informed outcomes-based assessment in clinical settings can transform personalized clinical care through multimodal treatments.

引用

页码：187 / 212

页数：26

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