Motor cortex - to act or not to act?

被引:95
作者
Ebbesen, Christian Laut [1 ,2 ]
Brecht, Michael [1 ,3 ]
机构
[1] Humboldt Univ, Bernstein Ctr Computat Neurosci Berlin, Linden 6, D-10099 Berlin, Germany
[2] Humboldt Univ, Berlin Sch Mind & Brain, Linden 6, D-10099 Berlin, Germany
[3] Humboldt Univ, NeuroCure Cluster Excellence, Linden 6, D-10099 Berlin, Germany
关键词
MEDIAL AGRANULAR CORTEX; PYRAMIDAL TRACT; CORTICAL ACTIVITY; FORELIMB REPRESENTATION; ELECTRICAL-STIMULATION; CORTICOSPINAL NEURONS; DESCENDING PATHWAYS; INHIBITORY CONTROL; PREFRONTAL CORTEX; ACTION INITIATION;
D O I
10.1038/nrn.2017.119
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The motor cortex is a large frontal structure in the cerebral cortex of eutherian mammals. A vast array of evidence implicates the motor cortex in the volitional control of motor output, but how does the motor cortex exert this 'control'? Historically, ideas regarding motor cortex function have been shaped by the discovery of cortical 'motor maps' - that is, ordered representations of stimulation-evoked movements in anaesthetized animals. Volitional control, however, entails the initiation of movements and the ability to suppress undesired movements. In this article, we highlight classic and recent findings that emphasize that motor cortex neurons have a role in both processes.
引用
收藏
页码:694 / 705
页数:12
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